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人脐带间充质干细胞向心肌样细胞定向分化及其临床移植研究进展
引用本文:刘明涛. 人脐带间充质干细胞向心肌样细胞定向分化及其临床移植研究进展[J]. 心血管病学进展, 2012, 33(2): 267-271
作者姓名:刘明涛
作者单位:遵义医学院,贵州遵义,563003
摘    要:人脐带间充质干细胞是一种非常有潜力的干细胞资源,在一定条件下可分化为骨、软骨、脂肪、神经、肝、心肌等多种组织细胞。因与其他来源干细胞相比,其资源丰富,不存在伦理道德问题,免疫原性弱,并已应用临床移植研究。现就人脐带间充质干细胞向心肌细胞的定向分化及其临床移植应用研究做简要综述。

关 键 词:脐带  间充质干细胞  心肌样细胞  临床移植

Human Umbilical Cord Mesenchymai Stem Cells Differentiation to Cardiomyocyte-like Cells Research
LIU Ming-tao. Human Umbilical Cord Mesenchymai Stem Cells Differentiation to Cardiomyocyte-like Cells Research[J]. Advances in Cardiovascular Diseases, 2012, 33(2): 267-271
Authors:LIU Ming-tao
Affiliation:1.Zunyi Medical College,Zunyi 563003,Guizhou,China;2.Sichuan Academy of Medical Sciences,Sichuan People’s Hospital,Chengdu 610072,Sichuan,China)
Abstract:Human umbilical cord mesenchymal stem cells(HUMSCs) are a very promising resource of stem cells.Under certain conditions these stem cells could differentiate into bone,cartilage,fat,nerves,liver,heart and other tissues.This is comparable to other types of stem cells.Unlike other types of stem cells,however,HUMSCs are less controversial.This article provides an overview of the process of differentiation of HUMSCs into cardiomyocytes,and their clinical application.
Keywords:human umbilical cord  mesenchymal stem cells  cardiomyocytes
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