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瑞芬太尼复合丙泊酚麻醉在经眶上锁孔入路切除鞍区巨大肿瘤中的应用
引用本文:远征,朱坚忠,黄文思.瑞芬太尼复合丙泊酚麻醉在经眶上锁孔入路切除鞍区巨大肿瘤中的应用[J].中国药房,2010(20):1856-1857.
作者姓名:远征  朱坚忠  黄文思
作者单位:海口市人民医院;中南大学湘雅医学院附属海口医院麻醉科;
摘    要:目的:探讨瑞芬太尼复合丙泊酚静脉麻醉在经眶上锁孔入路切除鞍区巨大肿瘤中的应用。方法:42例鞍区巨大肿瘤均行经眶上锁孔入路切除手术,随机分为2组,A组行瑞芬太尼复合丙泊酚持续泵注维持麻醉;B组行芬太尼复合丙泊酚持续泵注维持麻醉。分别记录2组平均动脉压、心率、呼气末二氧化碳分压、苏醒参数(睁眼时间、自主呼吸恢复时间、拔管时间)及术后并发症情况。结果:2组患者的麻醉过程平稳,均能顺利完成手术,麻醉效果满意。无1例术后出现麻醉相关并发症。但A组在插管后和拔管后血压、心率的变化小于B组(P<0.05);各项苏醒参数也优于B组(P<0.05)。结论:与芬太尼比较,瑞芬太尼复合丙泊酚静脉麻醉,诱导时间更短,麻醉维持期血流动力学更稳定,清醒快而完全,更适于经眶上锁孔入路鞍区巨大肿瘤切除手术。

关 键 词:瑞芬太尼  丙泊酚  鞍区巨大肿瘤  麻醉

Applications of Remifentanil and Propofol-inducing Anesthesia in Transsupraorbital Keyhole Approach for the Resection of Giant Pituitary Adenomas
YUAN Zheng,ZHU Jian-zhong,HUANG Wen-si.Applications of Remifentanil and Propofol-inducing Anesthesia in Transsupraorbital Keyhole Approach for the Resection of Giant Pituitary Adenomas[J].China Pharmacy,2010(20):1856-1857.
Authors:YUAN Zheng  ZHU Jian-zhong  HUANG Wen-si
Institution:(Haikou Municipal People’s Hospital, Haikou 570208, China) YUAN Zheng, ZHU Jian-zhong, HUANG Wen-si(Dept. of Anesthesiology, Haikou Hospital of Xiangya Medical College, Central South University, Haikou 570208, China)
Abstract:OBJECTIVE:To study the application of remifentanil and propofol-inducing intravenous anesthesia in transsupraorbital keyhole approach for the resection of giant pituitary adenomas. METHODS:42 patients with giant tumors in sellar region were randomized into 2 groups. Patients of 2 groups were intubated in respiration tract after intravenous anesthesia. Anesthesia was maintained with either remifentanil combined with propofol (group A) or fentanyl combined with propofol (group B) with continuous infusion. Mea...
Keywords:Remifentanil  Propofol  Giant pituitary adenomas in sellar region  Anesthesia  
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