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Risk of Left Ventricular Assist Device as a Bridge to Heart Transplant Following Postinfarction Ventricular Septal Rupture
Authors:Vibhu R Kshettry  MD    Christopher T Salerno  MD  Alan J Bank  MD
Institution:Cardiac Surgical Associates, P.A., Minneapolis Heart Institute, Minneapolis, Minnesota;Division of Cardiovascular and Thoracic Surgery, University of Minnesota Hospital and Clinic, Minneapolis, Minnesota
Abstract:A bstract Heart transplantation is an effective treatment for end-stage heart failure. However, due to the persistent shortage of donor hearts, many patients die awaiting a transplant. Implantable left ventricular assist devices are now available as a reliable bridge to cardiac transplantation. This report presents a patient with terminal heart failure as a result of a postmyocardial infarction ventricular septal rupture (VSR), who underwent a successful placement of the HeartMate left ventricular assist device (LVAD) and velour patch closure of an apical VSR. Despite this therapy, the patient expired after developing a second VSR, which created a high-flow right-to-left shunt and caused hypoxic irreversible brain injury. We suggest that use of a left ventricular assist device as a bridge to transplantation be approached with extreme caution in a patient with a postinfarction ventricular septal rupture.
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