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分光光度法测定磺咳合剂中磺胺嘧啶的含量
引用本文:尚尔宁,沈惠明,樊祥堃. 分光光度法测定磺咳合剂中磺胺嘧啶的含量[J]. 抗感染药学, 2004, 1(2): 84-85
作者姓名:尚尔宁  沈惠明  樊祥堃
作者单位:苏州市第二人民医院药剂科,江苏,苏州,215002;苏州市第二人民医院药剂科,江苏,苏州,215002;苏州市第二人民医院药剂科,江苏,苏州,215002
摘    要:目的:建立磺咳合剂中磺胺嘧啶的含量测定方法。方法:采用分光光度法测定磺胺嘧啶的含量,选定254nm为测定波 长,绘制工作曲线。结果:磺胺嘧啶在浓度为6~14μg·mL-1内呈线性范围,相关系数r=0.9998。浓度为7.0、10.0、13.0μg· mL-1样品液的平均回收率为:100.38%,RSD=0.91%。结论:本方法操作简便、快速、结果准确、精密度高。

关 键 词:磺咳合剂  分光光度法  磺胺嘧啶
文章编号:1672-7878(2004)02-0084-02

Determination of sulfadiazine content in sulfadiazine anticough mixture by spectrophotometry
SHANG Er-ning,SHEN Hui-ming,FAN Xiang-kun. Determination of sulfadiazine content in sulfadiazine anticough mixture by spectrophotometry[J]. Anti-infection Pharmacy, 2004, 1(2): 84-85
Authors:SHANG Er-ning  SHEN Hui-ming  FAN Xiang-kun
Abstract:Objective: To determine Sulfadiazine content in Sulfadiazine anticouph mixture. Methods: Spectrophotometry was used to determine Sulfadiazine content. The work-curve was made with detection wavelengths at 254nm. Results: The method was linear over the range of 6-14μ g·mL of Sulfadiazine concentrations(r=0.9998). The average recovery was 100.38%, RSD=0.91%. Conclusion: The method is simple rapid and accurate. It is suitable for the quality control of the hospital preparations.
Keywords:sulfadiazine anticough mixture  spectrophotometry  sulfadiazine  
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