A comparative assessment of the performance of a state-of-the art small footprint dedicated cardiovascular CT scanner |
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Authors: | Paul Maggiore Alex L. Huang Malcolm Anastasius Richard Brown Jordan Boroditsky Evan Ariel Jonah Ezekiel Jacob Merkur Philipp Blanke Jonathon Leipsic |
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Affiliation: | 1. Carcinoid Heart Disease Clinic, Department of Cardiology, Royal Free Hospital, London, United Kingdom;2. Department of Radiology, Royal Free Hospital, London, United Kingdom;3. Neuroendocrine Tumour Unit, ENETS Centre of Excellence, Royal Free Hospital, London, United Kingdom;1. Department of Cardiology, Friedrich-Alexander-University Erlangen-Nürnberg, Erlangen, Germany;2. Department of Cardiology, University Medical Center Mainz, Johannes-Gutenberg University Mainz, Mainz, Germany;1. Division of Cardiology, Department of Medicine, Duke University Medical Center, United States;2. Department of Biostatistics and Bioinformatics, Duke University Medical Center, United States;3. Division of Cardiothoracic Imaging, Department of Radiology, Duke University Medical Center, United States;4. Division of Cardiothoracic Surgery, Department of Surgery, Duke University Medical Center, United States |
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Abstract: | IntroductionWith increasing adoption of CT coronary angiography (CTA) there is increasing demand for cost-effective, small footprint, dedicated cardiac scanners. We compared a state-of-the-art, small footprint dedicated cardiac scanner (DCCT) to a standard multidetector scanner (MDCT).MethodsThe study was a retrospective unblinded single centre study. A total of 800 patients were included, with 400 undergoing a DCCT and MDCT coronary CTA scanning, respectively. Image quality was assessed using a 4-point grading score. Image noise and artifact, signal-to-noise ratio (SNR) and contrast-to-noise ratio (CNR), and acceptance rate for CT-derived fractional flow reserve (FFRct) were recorded.ResultsOverall image quality was higher in the DCCT group (3.8 ± 0.55 vs 3.6 ± 0.69; p = 0.042). There was no difference in overall image noise (p = 0.131) or artifact (p = 0.295). SNR was superior in the DCCT group (14.2 ± 6.85 vs 11.4 ± 3.32; p < 0.005) as was CNR (12.7 ± 6.77 vs 11.9 ± 3.29; p < 0.005). The heart rate was lower in the DCCT group (56 ± 9.1 vs 59 ± 8.1; p < 0.005). No difference in the dose length product (DLP median 244.53 (IQR 105.6) vs 237.63 (IQR 160.1); p = 0.313) or FFRCT acceptance rate (100 vs 97.7%; p > 0.05) was noted. Independent predictors of excellent quality regardless of scanner type were age (p = 0.011), heart rate <65 bpm (p < 0.005), and body mass index < 35 (p < 0.005).ConclusionA DCCT scanner is capable of image quality similar to modern current generation general purpose CT technology. Such technology appears to be a viable option to serve the increasing demand for CTCA imaging. |
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Keywords: | Dedicated cardiovascular CT FFRct CTCA Atherosclerosis Chest pain BPM" },{" #name" :" keyword" ," $" :{" id" :" kwrd0040" }," $$" :[{" #name" :" text" ," _" :" Beats per minute BMI" },{" #name" :" keyword" ," $" :{" id" :" kwrd0050" }," $$" :[{" #name" :" text" ," _" :" Body Mass Index CTCA" },{" #name" :" keyword" ," $" :{" id" :" kwrd0060" }," $$" :[{" #name" :" text" ," _" :" Computer Tomography Coronary Angiography (CTCA) DCCT" },{" #name" :" keyword" ," $" :{" id" :" kwrd0070" }," $$" :[{" #name" :" text" ," _" :" Dedicated Cardiovascular CT HU" },{" #name" :" keyword" ," $" :{" id" :" kwrd0080" }," $$" :[{" #name" :" text" ," _" :" Hounsfield unit LM" },{" #name" :" keyword" ," $" :{" id" :" kwrd0090" }," $$" :[{" #name" :" text" ," _" :" Left main coronary artery LAD" },{" #name" :" keyword" ," $" :{" id" :" kwrd0100" }," $$" :[{" #name" :" text" ," _" :" Left anterior descending coronary artery LCx" },{" #name" :" keyword" ," $" :{" id" :" kwrd0110" }," $$" :[{" #name" :" text" ," _" :" Left circumflex coronary artery MDCT" },{" #name" :" keyword" ," $" :{" id" :" kwrd0120" }," $$" :[{" #name" :" text" ," _" :" Multidetector CT SCCT" },{" #name" :" keyword" ," $" :{" id" :" kwrd0130" }," $$" :[{" #name" :" text" ," _" :" Society of Cardiovascular Computed Tomography SNR" },{" #name" :" keyword" ," $" :{" id" :" kwrd0140" }," $$" :[{" #name" :" text" ," _" :" Signal-to-noise-ratio CNR" },{" #name" :" keyword" ," $" :{" id" :" kwrd0150" }," $$" :[{" #name" :" text" ," _" :" Contrast-to-Noise ratio |
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