IMPORTANCE OF DONOR SELECTION IN RENAL TRANSPLANTATION |
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| Authors: | NK MEHRA GS CHOPRA |
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| Institution: | *Prof & Head, Histocompatibility and Immunogenetics Department, All India Institute of Medical Sciences, New Delhi-110029;+Classified Specialist Pathology, presently on study leave at the Histocompatibility and Immunogenetics Department, All India Institute of Medical Sciences, New Delhi-110029 |
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| Abstract: | Renal transplantation has become a treatment of choice for patients with end stage renal disease. A successful transplant is the result of a combination of several factors acting synergistically, such as the degree of HLA compatibility between donor and the recipient, pretransplant blood transfusions, the recipient''s state of immunoreactivity and sensitization, immunosuppressive therapy given in post operative period etc. Donor selection appears to be the most critical factor for the long term success of the organ graft. In this brief review, some of the important parameters of donor selection in renal transplantation are highlighted.KEY WORDS: Histocompatibility (HLA) matching, Cross match, Sensitization |
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