颈动脉粥样硬化与血脂LDL／HDL-C及ApoB／ApoA1的关系

目的：研究颈动脉粥样硬化与血脂LDL／HDL—C及ApoB／ApoA1的关系。方法：对76例患者进行颈动脉超声检查，采用日立7600全自动生化测定仪测量LDL、HDL-C、ApoB、ApoA1、LDL／HDL—C及ApoB／ApoA1值的变化。结果：观察组和对照组患者的LDL和HDL—C之闯差异不明显（P〉0．05），LDL／HDL—C和AapoB／ApoA1的比值差异非常显著（P〈O．05），血糖与纤维蛋白原的值也非常显著（P〈0．05），且颈动脉粥样硬化程度与LDL／HDL—C、ApoB／ApoA1的比值存在显著相关性（P〈0．05）。结论：颈动脉粥样斑块的形成与血总胆固醇和低密度脂蛋白、栽脂蛋白B的指标增高有关。

Study on the Relationship between Blood Lipid LDL/HDL-C and ApoB/ApoA1 and Carotid Atherosclerosis

Objective： To study the relationship between blood lipid LDL/HDL-C and ApoB/ApoA1 and carotid atheroselerosis. Method： 76 patients were investigated by ultrasonic apparatus to detect carotid atherosclerosis, to detect the value of LDL, HDL-C, ApoB ,ApoAl , LDL/HDL-C and ApoB/ApoA1 by au- tomatic biochemistry analyzer of Hitachi 7600. Result： There were no significant difference in LDL and HDL -C between the carotid atherosclerosis group and the control group （ P〉0.05 ）. The ratios of LDL/HDL-C and ApoB/ApoA1 were significant different between the two groups （ P 〈0.05 ）. The value of blood sugar and hemaleuein were significant different between the two groups （ P 〈0.05 ）, and the ratios of LDL/HDL- C and ApoB/ApoA1 were associated with carotid atheroselerosis （P〈0.05）. Conclusion： The formation of carotid plaque is related to increase the total blood cholesterol, low density lipoprotein and apolipoprotein B.