无创正压通气治疗慢性阻塞性肺疾病并呼吸衰竭的临床观察

目的:探讨无创正压通气(non-invasive positive pressure ventila-tion,NIPPV)在治疗慢性阻塞性肺疾病(COPD)中的临床作用。方法:选取我院2009年1月～2010年3月间收治的急性加重并呼吸衰竭的患者100例,随机分为治疗与对照两组,治疗组,在常规治疗基础上予NIPPV(予BiPAP呼吸机辅助通气),对照组予鼻导管吸氧,对比两组患者临床症状和血气改善情况。结果:治疗组患者的临床症状和血气情况较对照组有显著改善,组间比较差异显著(P<0.05)。结论:无创呼吸机可以迅速减轻COPD急性加重并呼吸衰竭患者的二氧化碳潴留,缓解呼吸困难,避免或减少气管插管。

Effects of noninvasive positive pressure ventilation on chronic obstructive pulmonary disease

Objective: To investigate the effects of noninvasive positive pressure ventilation(non-invasive positive pressure ventila-tion,NIPPV) on chronic obstructive pulmonary disease(COPD).Methods: A total of 100 patients that were admitted to our hospital due to acute deterioration of COPD complicated with respiratory failure and treated during January 2009 to March 2010 were randomly divided into treatment group and control group which were treated with conventional therapy plus NIPPV therapy and nasal oxygen catheter,respectively.Improvements in clinical symptoms and blood gas indexes were compared between the two groups.Results: Improvements in clinical symptoms and blood gas indexes of the treatment group were significant better than that of the control group(P all <0.05).Conclusion: Non-invasive ventilator can quickly relieve acute exacerbation of COPD and respiratory failure in patients suffered from acute deterioration of COPD complicated with respiratory failure,thus can relieve breathing difficulties and avoid intubation.