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Placental transfer of pesticides in humans
Authors:M. C. Saxena Ph. D.   F.I.C.S.  M. K. J. Siddiqui  A. K. Bhargava  C. R. Krishna Murti  D. Kutty
Affiliation:(1) Industrial Toxicology Research Centre, Post Box No. 80, 226001 Lucknow, India;(2) Department of Obstetrics and Gynaecology, King George's Medical College, Lucknow, India
Abstract:Transfer of organochlorine pesticides from mother to fetus has been studied in 100 women. The concentrations of organochlorine pesticides were examined in maternal blood, placenta, and umbilical cord blood of the same mother/child pair. Residue levels of dichlorodiphenyl trichloro ethane (DDT) and its metabolites, isomers of benzene hexachloride (BHC) and aldrin were detected in all the samples analyzed, indicating their transfer from mother to the fetus. A correlation was found to exist between the pesticide concentration and age, dietetic habits and area of residence of pregnant women.
Keywords:Placenta  Umbilical cord  Organochlorine pesticides  DDT  BHC  Aldrin  Gas-liquid chromatograph
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