| 2型糖尿病不同中医证型红细胞Ins-RTPK活性变化机理探讨 |
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| 引用本文： | 祁建生,张恩平,李秀娟,汪碧萍,吴作干.2型糖尿病不同中医证型红细胞Ins-RTPK活性变化机理探讨[J].浙江中西医结合杂志,2002,12(2):71-73. |
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| 作者姓名： | 祁建生 张恩平 李秀娟 汪碧萍 吴作干 |
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| 作者单位： | 福建省中医药研究院,福州,350003 |
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| 基金项目： | 福建省自然科学基金资助项目 ( 1999～ 2 0 0 2 ) 0 9910 0 14 |
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| 摘 要： | 目的 :研究 2型糖尿病病人不同中医证型红细胞 Ins- RTPK活性变化。方法 :对 2型糖尿病 1 0 8例分别进行中医辨证分型 ,另设正常对照 3 0例 ,分别测定红细胞 Ins- RTPK活性及 2 4 h尿1 7- OHCS排出量。结果 :中医各证型红细胞 Ins- RTPK活性下降 ,其变化规律呈气滞血瘀型≌阴虚热盛型 >气阴两虚型 >阴阳两虚型 ;各证型 2 4 h尿 1 7- OHCS也有一定改变。结论 :不同中医证型的实验室变化说明 2型糖尿病病理机制与下丘脑 -垂体 -肾上腺皮质轴的功能改变有关。
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| 关 键 词： | 2型糖尿病 胰岛素受体 胰岛素受体酪氨酸蛋白激酶 肾上腺皮质 |
| 修稿时间： | 2001年5月28日 |
Mechanism Exploration of Type Ⅱ Diabetes Cases with Different TCM Diagnosis |
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| Qi Jiansheng,Zhang Enping,L i X iujuan,et al..Mechanism Exploration of Type Ⅱ Diabetes Cases with Different TCM Diagnosis[J].Zhejiang Journal of Integrated Traditional Chinese and Western Medicine,2002,12(2):71-73. |
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| Authors: | Qi Jiansheng Zhang Enping L i X iujuan |
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| Institution: | Qi Jiansheng,Zhang Enping,L i X iujuan,et al.The TCM Research institute of Fujian Province,Fuzhou35 0 0 0 3 |
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| Abstract: | Objective:To explore the changes of Ins- RTPK of red blood cells in type diabetes cases.Methods: 10 8type II diabetes cases were diagnosed based on TCM differential diagnosis with another30 cases as the control. Detections were m ade on the Ins- RTPK activity and 2 4hour urine17- OHCS levels.Results:The Ins- RTPK activity of red blood cells was reduced in all the cases which was more significant in the following order:Qi stagnation and blood stasis cases,Yin weakness and too much heat cases,weakness of both Qi and Yin,Yin and Yan weakness cases.17- OHCH change was also observed in different TCM diagnosis type diabetes cases. Conclusion:The lab test changes in different type diabetes cases indicated that it was related to the hypothalamus- hypophysis- adrenal gland functions. |
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| Keywords: | Type Diabetes Insulin receptor Tyrosine protease Adrenal cortex |
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