DepoGeston长效避孕针临床试验研究

目的:探讨DepoGeston长效避孕针常规使用的有效率、续用率、副反应。方法:采用临床试验研究,筛选接纳402例对象,每隔90±7天注射DepoGeston 150mg,于第一次注射后的3、6、9、12个月进行随访,观察1年。结果:402例对象使用DepoGeston 4619.0妇女月,平均每例使用11.5妇女月。研究过程中无一例意外妊娠发生,1年累积有效率为100％,续用率92.29％。对体重、血压影响不显著,大多数妇女对使用DepoGeston的总体评价良好。讨论:DepoGeston避孕有效率高,在为使用对象提供良好咨询和服务的条件下,可提高续用率,可提高使用妇女的生殖健康水平。

Clinical Study on the Effect of Long-acting Injectable Contraceptive-DepoGeston in ShanXi Province for Women

Objective: To evaluate the safety efficiency, continuation and acceptability of long - acting in-jectable contraceptive - DepoGeston for normal using among childbearing - aged women. Method: 402 sub-jects were injected DepoGeston injectable contraceptive every 90±7days for one year and were followed -up. The following - up was taken every three months after the first injection. Results: In the course of stud-y, 4619. 0 women - month and 11. 5 women - month per women were observed, There were no accident pregnancy occured, the use - effectiveness rate was 100% and the cumulative continuation rate was 92. 29%. There were no significant adverse effects on body weight and blood pressure. The main side effects were spotting, prolonged bleeding and amenorrhea. Majority women are satisfaeted with DepoGeston inject-able contraceptive. Discussion: DepoGeston injectable contraceptive was not only long -time using, but also safe and effective. The women of Shanxi province are suitable for DepoGeston injectable contraceptive. The use of DepoGeston can be beneficial to the procreation and health of the women.