氟中毒对骨生物力学性质影响实验研究

目的 研究了正常和氟中毒大鼠股骨的力学性质。方法 选用170—250g，3—4个月龄Wistar大鼠40只，随机分为正常对照组20只，模型组20只，对模型组大鼠经饮水投氟复制大鼠氟中毒模型。饲养3个月后处死大鼠，对大鼠股骨进行拉伸、弯曲、剪切、冲击实验。结果 得出了正常对照组和模型组的拉伸应力、应变，弹性模量；弯曲实验弯曲应力；剪切实验破坏载荷、剪应力；冲击实验冲击功，冲击韧性等指标。结论 模型组各项力学性能指标显低于正常对照组(P＜0．05)。

Experimental study on the F poisoning effect on the biomechanical nature of bone

Objective In this paper we did research on the mechanical natures of the normal and the F poisoning femoris of big rats.Method Divided 40 wistar b ig rats(170 to 250 g,3 to 4 months old)at random into the normal group and the m odel group,each group had 20 ones.Let the model group rats drink water poisoned by F.Executed all the rats 3 months later.Did the pull,bend,cut,impact tests on the two groups.Result Then we got the pulling stress,strain and modulus of elast ic,bending stress,cutting destructive load and stress,impacting work and tenacit y of the two groups.Conclusion The results of these tests showed that all the bi omechanical natures of the model group were strikingly lower than those of the n ormal group(P< 0.05).