| 单侧髁突切除对非手术侧髁突软骨细胞凋亡的影晌 |
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| 引用本文： | 廖立凡,罗应伟,李松,李玲玲.单侧髁突切除对非手术侧髁突软骨细胞凋亡的影晌[J].昆明医学院学报,2011,32(2):16-19. |
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| 作者姓名： | 廖立凡 罗应伟 李松 李玲玲 |
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| 作者单位： | 昆明医学院口腔医学院,云南昆明,650031 |
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| 基金项目： | 云南省教育厅科学研究基金资助项目 |
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| 摘 要： | 目的研究兔单侧髁突切除对非手术侧髁突软骨细胞凋亡活性的影响．方法24只5-6月龄的日本大耳白兔被随机分为两组：对照组和手术组．手术组通过手术切除-侧髁突建立动物模型，分别于术后2个月、4个月采用TUNEL染色，观察非手术侧髁突软骨中凋亡细胞数的表达．结果对照组相比，手术组单侧髁突切除2月和4月后非手术侧髁突软骨凋亡细胞数均增加（P〈0.05），但物手术组4月较2月增加明显（P〈0.05）．结论单侧髁突切除可导致非手术侧髁突软骨凋亡细胞数量增加．
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| 关 键 词： | 髁突切除 软骨 凋亡 |
Effect of Unilateral Condylectomy on the Cell Apoptosis of Condylar Cartilage on the Opposite Side |
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| LIAO Li-fan,LUO Ying-wei,LI Song,LI Ling-ling.Effect of Unilateral Condylectomy on the Cell Apoptosis of Condylar Cartilage on the Opposite Side[J].Journal of Kunming Medical College,2011,32(2):16-19. |
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| Authors: | LIAO Li-fan LUO Ying-wei LI Song LI Ling-ling |
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| Institution: | LIAO Li-fan,LUO Ying-wei,LI Song,LI Ling-ling(The Stomatology Collegy of Kunming Medical University,Kunming Yunnan 650031,China) |
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| Abstract: | Objective To investigate the effect of unilateral condylectomy on the cell apoptosis of condylar cartilage on the opposite side. Methods Twenty four 5-6 months old Japanese big ear rabbits were randomly divided into 2 groups： the control group and the operation group. The opetation group was created by removing the right condylar process. The left condylar cartilage was dissected 2 months and 4 months after the operation, and TUNEL was used to detect the apoptotie cell. Result Compared with the control group, the number of apoptotic cells increased significantly in operation group 2 months and 4 months after operation （P 〈 0.05） , and the increase 4 months after operation was more significant than the 2 months after operation （P 〈 0.05 ）. Conclusion Unilateral condylectomy will increase the number of apoptotic cells of the condylar cartilage on the opposite side. |
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| Keywords: | Condylectomy Cartilage Apoptosis |
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