脑损伤患者语义启动效应的研究

目的探讨脑损伤患者语义启动效应的变化。方法对8例阿尔茨海默病(AD)患者、15例血管性痴呆(VD)患者、17例脑外伤(TBI)患者、24名正常青年人(青年组)、17名正常中老年人(中老年组)进行简易精神状态检查、临床记忆量表、加工分离程序测验,对所得数据进行统计学分析。结果AD组患者的意识性提取、自动提取成绩均显著低于青年组及中老年组(P<0.001);VD组、TBI组患者的意识性提取成绩均显著低于青年组及中老年组(P<0.001),自动提取成绩与青年组及中老年组的差异无显著性意义(P>0.05)。结论AD患者的外显记忆和语义启动效应损伤,VD和TBI患者的外显记忆损伤,语义启动效应均保留。

Study of Semantic Priming Effect in Patients with Brain Injury

Objective To investigate the changes of the semantic priming effect in patients with brain injury.Methods Eight patients with Alzheimer's disease(AD),fifteen patients with vascular dementia(VD),seventeen patients with traumatic brain injury (TBI),twenty four healthy young subjects,and seventeen elderly healthy subjects as normal controls were estimated by Mini-Mental State Examination(MMSE),clinical memory scale,and process dissociation procedure(PDP) tasks.The data of all subjects were analyzed.Results The patients in the AD group had lower recollection and automatic scores than those in the young and elderly control groups in free association task(P<0.05~0.001).The recollection scores in the VD and TBI groups decreased significantly when compared with that in the young and elderly control groups in free association tasks(P<0.001),whereas the automatic scores had no significant difference among four groups(P>0.05).Conclusion AD patients exhibited impaired explicit memory and semantic priming effect,but retain normal perceptual priming effect;VD and TBI patients showed impaired explicit memory,but retained normal semantic priming effect.