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慢性肝炎患者血清甘胆酸与其肝组织炎症病理分度的相关性研究
引用本文:刘伟,赵伟,耿全林,罗婵.慢性肝炎患者血清甘胆酸与其肝组织炎症病理分度的相关性研究[J].天津医药,2001,29(10):604-605.
作者姓名:刘伟  赵伟  耿全林  罗婵
作者单位:南京东南大学医学院附属南京第二医院,
摘    要:目的:探讨慢性肝炎患者血清甘胆酸与其在肝组织炎症病理分度(G)的相关性。方法:随机选择50例慢性肝炎患者,抽静脉血检测其血清甘胆酸,并行肝组织活检、病理检查。结果:肝组织炎症活动度越高,血清甘胆酸升高愈明显,G1与G2、G2与G3、G3与G4之间比较,呈现显著性差异(P<0.05),G与血清CA两者关系密切。结论:血清甘胆酸是观察慢性肝炎患者肝组织炎症变化的较敏感而准确的指标。

关 键 词:肝炎  慢性病  甘胆酸  炎症

The Study on the Relationship between Serum CA and Liver Tissue lnflammation Activity in Chronic Hepatitis
LIU Wei,ZHAO Wei,GENG Quanlin,et al.The Study on the Relationship between Serum CA and Liver Tissue lnflammation Activity in Chronic Hepatitis[J].Tianjin Medical Journal,2001,29(10):604-605.
Authors:LIU Wei  ZHAO Wei  GENG Quanlin  
Institution:LIU Wei,ZHAO Wei,GENG Quanlin,et al Department of Pathology,the Affiliated Nanjing Second Hospital of Nanjing Dongnan University,Nanjing 210003
Abstract:Objective: To study the relationship between serum conjugated bile acids (CA) and liver tissue inflammation activity in chronic hepatitis. Methods: Serum CA and liver tissue inflammation activity were examined with pathological method in 50 patients with chronic hepatitis. Results: With the liver tissue inflammation activity elevated, the serum CA increased. The serum CA was significantly correlated with the liver inflammation activity (G) in chronic hepatitis B (P<0.05). Conclusion: Serum CA is a sensitive marker for liver tissue inflammation activity in patients with chronic hepatitis.
Keywords:hepatitis chronic disease glycocholic acid liver inflammation
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