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Tracking human neurologic disease status in mouse brain/plasma using reporter-tagged,EV-associated biomarkers
Affiliation:1. Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA;2. The Collaborative Center for X-linked Dystonia-Parkinsonism, Massachusetts General Hospital, Charlestown, MA 02129, USA;3. Center for Molecular Imaging Research, Department of Radiology, Massachusetts General Hospital and Program in Neuroscience, Harvard Medical School, Boston, MA 02114, USA
Abstract:
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  • Keywords:Extracellular vesicles  xenograft model  X-linked dystonia-parkinsonism  TAF1-32i  human iPSC-derived neural progenitor cells  brain  biomarkers  neurologic disease
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