The role of transanal drainage tube in preventing the anastomotic leakage in rectal cancer surgery without a defunctioning stoma: A meta-analysis |
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| Affiliation: | 1. Gastric and Colorectal Surgery Division, Department of General Surgery, Daping Hospital, Army Medical University, No. 10, Changjiangzhilu, Daping, Yuzhong District, Chongqing, 400042, China;2. Gastric Cancer Center, Laboratory of Gastric Cancer, State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University, Chengdu, Sichuan Province, China;1. Department of General Surgery, Faculty of Medicine, Minia University, Egypt;2. Department of General Surgery, Faculty of Medicine, Misr University for Science and Technology, Egypt;1. Department of Clinical Epidemiology and Biostatistics, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, Thailand;2. Department of Surgery, Faculty of Medicine Vajira Hospital, Navamindradhiraj University, Bangkok, Thailand;3. Information Technology Department, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, Thailand;4. Department of Surgery, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, Thailand;5. Centre for Public Health, School of Medicine, Dentistry, and Biomedical Sciences, Queen''s University Belfast, Northern Ireland, UK;6. Centre for Clinical Epidemiology and Biostatistics, Hunter Medical Research Institute, School of Medicine and Public Health, The University of Newcastle, New Lambton, New South Wales, Australia;1. Department of Surgery, Queen Elizabeth Hospital, HKSAR Hong Kong;2. Multi-Disciplinary Simulation and Skills Centre (MDSSC), Queen Elizabeth Hospital, HKSAR Hong Kong;3. Department of Anaesthesiology & Operating Theatre Services, Queen Elizabeth Hospital, HKSAR Hong Kong;4. Intensive Care Unit, Queen Elizabeth Hospital, HKSAR Hong Kong |
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| Abstract: | BackgroundAnastomotic leakage is a common and serious complication after rectal cancer surgery. The role of transanal drainage tube (TDT) in the prevention of anastomotic leakage is still controversial. The aim of this study was to evaluate the role of TDT in preventing anastomotic leakage.MethodsTwo reviewers individually searched the PubMed, Embase and Cochrane Library ranging from January 2000 to June 2022. The pooled odds ratio (ORs) and weighted mean difference (WMD) with the 95% confidence interval (95% CI) were used to assess anastomotic leakage and other parameters.ResultsA total of 3383 patients (1508 in the TDT group and 1875 in the cohort study group) were included in 13 studies. The study found that patients treated with TDT had a lower incidence of anastomotic leakage with or without neoadjuvant radiotherapy. Moreover, patients who received TDT had lower rates of reoperation and tended to reduce the severity of anastomotic leakage.ConclusionsFor rectal cancer patients without defunctioning stoma, TDT could reduce the incidence of anastomotic leakage, decrease the reoperation rate of patients, and tend to reduce the severity of anastomotic leakage. More RCT are needed to assess the role of TDT in rectal cancer surgery. |
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| Keywords: | Anastomotic leakage Transanal drainage tube Rectal cancer Prevention Efficacy |
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