Profile of and risk factors for early unplanned readmissions in patients with acute necrotizing pancreatitis |
| |
| Institution: | 1. Department of Internal Medicine, Indiana University School of Medicine, Indianapolis, IN, USA;2. Division of Gastroenterology and Hepatology, Indiana University School of Medicine, Indianapolis, IN, USA;3. Department of Biostatistics, Indiana University School of Medicine, Indianapolis, IN, USA;4. Department of Surgery, Indiana University School of Medicine, Indianapolis, IN, USA;1. Department of General Surgery, Faculty of Medicine, Mersin University, Mersin, Turkey;2. Department of Radiology, Faculty of Medicine, Mersin University, Mersin, Turkey;1. Yale University School of Medicine, New Haven, CT, USA;2. University Medicine Greifswald, Greifswald, Germany;3. VA CT Healthcare System, West Haven, USA;4. Memorial Sloan Kettering Cancer Center, New York, USA;5. LMU University Hospital Munich, Germany;7. CH Cornouaille, Quimper, France;8. Beaujon Hospital, Clichy, France;9. Dupuytren University Hospital, Limoges, France;10. CHU Rangueil, Toulouse, France;11. Hôpital Tenon (AP-HP), Paris, France;12. CHU Nantes, Nantes, France;13. CH Cholet, Cholet, France;14. Hospital of Saint-Etienne, Saint-Etienne, France;15. CHI d''Aulnay-sous-Bois, Aulnay-sous-Bois, France;p. Avignon Hospital, Avignon, France;q. Le Havre Hospital, Le Havre, France;r. Hospital of Saint-Etienne, St-Etienne, France;s. University Hospital Croix Rousse, Lyon, France;t. HIA Clermont-Tonnerre, Brest, France;u. CHU Estaing, Clermont Ferrand, France;v. CH Saint Brieuc, Saint-Brieuc, France;w. CHU Reims, Reims, France;x. Saint Antoine Hospital, Paris, France;y. CHR Orléans, Orléans, France;z. CHRU Strasbourg, Strasbourg, France;11. CHU Brest, Brest, France;12. Hôpital Antoine-Béclère, Clamart, France;13. Hôpital Louis Mourier, Colombes, France;14. CH Cahors, Cahors, France;15. CHU Clermont-Ferrand, Clermont-Ferrand, France;16. CH Chartres, Chartres, France;17. CHU Dijon, Dijon, France;18. CHU Grenoble, Grenoble, France;19. Hôpital Pasteur, Colmar, France;110. CH Saint-Malo, Saint-Malo, France;111. Pellegrin-Enfants Hospital, Bordeaux, France;112. Hôpital de la Timone Enfants, Marseille, France;113. CH Blois, Blois, France;114. Archet II Hospital, Nice, France;115. CH des Escartons, Briançon, France;1p. Hôpital privé Jean Mermoz, Lyon, France;1q. Hôpital de Mulhouse, Mulhouse, France;1r. Institut Paoli Calmettes, Marseille, France;1s. CHU Rennes, Rennes, France;1t. Timone University Hospital, Marseille, France;1u. CH Bretagne Atlantique, Vannes, France;1v. CH Dax-Côte d''Argent, Dax, France;1w. GH Diaconesses, Paris, France;1x. CHI Villeneuve Saint Georges, Créteil, France;1y. Hôpital Femme Mère Enfant, Bron, France;1z. CH Chartres, Le Coudray, France;21. Hôpital d''instruction des armées Percy, Clamart, France;22. Beaujon Hospital, Paris, France;23. University Hospital of Besançon, Besançon, France;24. Clinique Sainte Barbe, Strasbourg, France;25. CHU Poitiers, Poitiers, France;26. CHU Amiens, Amiens;27. Rouen University Hospital, Rouen, France;28. Trousseau Hospital, Tours, France;29. Angers University Hospital, Angers, France;210. Bichat Hospital, Paris, France;211. Edouard Herriot Hospital, Lyon, France;212. CH Saint Joseph Saint Luc, Lyon, France;213. CHI de Créteil, Créteil, France;214. Clinique Charcot, Saint Foy les Lyon, France;215. Hôpital Dreux, Dreux, France;2p. CHU Bordeaux, Bordeaux, France;2q. Poitiers University Hospital, Poitiers, France;2r. CH Melun, Melun, France;2s. Hôpital Saint-Eloi, Montpellier, France;2t. CH Bastia, Bastia, France;1. Univ Brest, Inserm, EFS, UMR 1078, GGB, F-29200, Brest, France;2. Service de Génétique Médicale et de Biologie de la Reproduction, CHRU Brest, F-29200, Brest, France;3. Service de Pédiatrie, Hépato-Gastro-Entérologie et Nutrition Pédiatrique, Hôpitaux Pédiatriques de Nice CHU Lenval, Nice, France;4. Service d''Hépato-Gastroentérologie et Assistance Nutritionnelle, Institut des Maladies de l''Appareil Digestif (IMAD), Centre Hospitalo-Universitaire (CHU), Nantes, France;5. Institute of Medical Genetics, School of Medicine, Cardiff University, Cardiff, United Kingdom;6. Pancreatology and Digestive Oncology Department, Beaujon Hospital, APHP - Clichy, Université Paris Cité, Paris, France;1. Department of Pathology, Jichi Medical University, 3311-1 Yakushiji, Shimotsuke, 329-0498, Japan;2. Department of Medicine, Division of Gastroenterology, Jichi Medical University, 3311-1 Yakushiji, Shimotsuke, 329-0498, Japan;3. Shinozaki Medical Clinic, 6-1-13 Kiyoharadai, Utsunomiya, 321-3223, Japan;4. Photon Science Center, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, 113-0033, Japan;1. Division of Gastroenterology, Hepatology, and Nutrition, Cincinnati Children''s Hospital Medical Center, Cincinnati, OH, USA;2. Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH, USA;3. Department of Radiology, Cincinnati Children''s Hospital Medical Center, Cincinnati, OH, USA;4. Department of Mathematical Sciences, University of Cincinnati, Cincinnati, OH, USA;5. Division of Biostatistics and Epidemiology, Cincinnati Children''s Hospital Medical Center, Cincinnati, OH, USA;6. Department of Radiology, University of Cincinnati College of Medicine, Cincinnati, OH, USA |
| |
| Abstract: | IntroductionAcute necrotizing pancreatitis (ANP) complicates up to 15% of acute pancreatitis cases. ANP has historically been associated with a significant risk for readmission, but there are currently no studies exploring factors that associate with risk for unplanned, early (<30-day) readmissions in this patient population.MethodsWe performed a retrospective review of all consecutive patients presenting to hospitals in the Indiana University (IU) Health system with pancreatic necrosis between December 2016 and June 2020. Patients younger than 18 years of age, without confirmed pancreatic necrosis and those that suffered in-hospital mortality were excluded. Logistic regression was performed to identify potential predictors of early readmission in this group of patients.ResultsOne hundred and sixty-two patients met study criteria. 27.7% of the cohort was readmitted within 30-days of index discharge. The median time to readmission was 10 days (IQR 5–17 days). The most frequent reason for readmission was abdominal pain (75.6%), followed by nausea and vomiting in (35.6%). Discharge to home was associated with 93% lower odds of readmission. We found no additional clinical factors that predicted early readmission.ConclusionPatients with ANP have a significant risk for early (<30 days) readmission. Direct discharge to home, rather than short or long-term rehabilitation facilities, is associated with lower odds of early readmission. Analysis was otherwise negative for independent, clinical predictors of early unplanned readmissions in ANP. |
| |
| Keywords: | Early readmission Acute necrotizing pancreatitis Pancreatic necrosis |
| 本文献已被 ScienceDirect 等数据库收录！ |
|
