| 速度向量成像技术评价大鼠腹主动脉硬化管壁运动 |
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| 引用本文： | 王丹军,王峰,陈芸,鲁树坤,梁银婷,王玥,石宇,胡正明. 速度向量成像技术评价大鼠腹主动脉硬化管壁运动[J]. 中国医学影像技术, 2010, 26(1): 40-43 |
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| 作者姓名： | 王丹军 王峰 陈芸 鲁树坤 梁银婷 王玥 石宇 胡正明 |
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| 作者单位： | 1. 北京大学深圳医院超声影像科,广东,深圳,518036
2. 深圳湘雅医药研究院,广东,深圳,518057 |
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| 摘 要： | 目的 应用速度向量成像(VVI)技术评价大鼠腹主动脉硬化不同时期管壁运动特征.方法 选择健康SD大鼠24只,基础喂养1周后开始高脂喂养.分别于高脂喂养前、高脂喂养第8、12周末测量大鼠腹主动脉内中膜厚度(IMT)、收缩末期血管内径(Ds),血流收缩期峰值流速(Vs)、阻力指数(RI)、搏动指数(PI);应用VVI技术检测动脉管壁的最大峰值运动速度(V_(max))、最大应变(S_(max))及最大应变率 (SR_(max)).结果 高脂喂养8周末腹主动脉内膜欠光滑或不光滑,光镜下见少量泡沫细胞,S_(max)、SR_(max)与高脂喂养前比较明显减低(P<0.05).高脂喂养12周末IMT增厚,部分可见粥样硬化斑块形成,动脉IMT、Ds、Vs、RI、PI与高脂喂养前比较差异均有统计学意义(P<0.05);V_(max)、S_(max)、SR_(max)与高脂喂养前、高脂喂养8周末比较均明显减低(P<0.05).结论 VVI技术可定量评价大鼠动脉硬化不同时期血管壁弹性功能的改变.
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| 关 键 词： | 速度向量成像 超声检查 腹主动脉 动脉硬化 |
| 收稿时间： | 2009-06-20 |
| 修稿时间： | 2009-09-30 |
Velocity vector imaging evaluation of abdominal aorta atherosclerosis wall motion in rats |
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| WANG Dan-jun,WANG Feng,CHEN Yun,LU Shu-kun,LIANG Yin-ting,WANG Yue,SHI Yu and HU Zheng-ming. Velocity vector imaging evaluation of abdominal aorta atherosclerosis wall motion in rats[J]. Chinese Journal of Medical Imaging Technology, 2010, 26(1): 40-43 |
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| Authors: | WANG Dan-jun WANG Feng CHEN Yun LU Shu-kun LIANG Yin-ting WANG Yue SHI Yu HU Zheng-ming |
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| Affiliation: | Department of Ultrasound, Shenzhen Hospital of Peking University, Shenzhen 518036, China;Shenzhen Institute of Xiangya Pharmaceutics, Shenzhen 518057, China;Department of Ultrasound, Shenzhen Hospital of Peking University, Shenzhen 518036, China;Department of Ultrasound, Shenzhen Hospital of Peking University, Shenzhen 518036, China;Department of Ultrasound, Shenzhen Hospital of Peking University, Shenzhen 518036, China;Department of Ultrasound, Shenzhen Hospital of Peking University, Shenzhen 518036, China;Department of Ultrasound, Shenzhen Hospital of Peking University, Shenzhen 518036, China;Department of Ultrasound, Shenzhen Hospital of Peking University, Shenzhen 518036, China |
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| Abstract: | Objective To evaluate the characteristics of abdominal aorta wall motion in different stages of rats atherosclerosis with velocity vector imaging(VVI)technique.Methods Twenty-four healthy SD rats were on high-fat feeding after one week ordinary diet.Abdominal aortic intima-media thickness(IMT),end-systolic blood vessel diameter(Ds),peak systolic velocity(Vs),resistance index(RI),pulsatility index(PI)were measured before and at the end of 8th and 12nd week.Artery wall peak velocity(V max),maximum tangential ... |
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| Keywords: | Velocity vector imaging Ultrasonography Abdominal aorta Arteriosclerosis |
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