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Monitoring the pathophysiological correlates of postmenopausal hot flushes
Authors:R.W. Silverman  J.G. Bajorek  P. Lomax  I.V. Tataryn
Affiliation:1. Department of Pharmacology, School of Medicine and the Brain Research Institute, University of California, Los Angeles, CA 90024, U.S.A.;2. Department of Obsterics and Gynecology, University of Alberta, Edmonton, Alberta T6G 2B7, Canada
Abstract:Clinical assessment of the severity and frequency of post-menopausal hot flushes can be made objectively by measuring the associated changes in skin conductance and skin and core temperature. Such measurements provide a more reliable index of the response to therapy than does subjective reporting which has been employed in the past. The design and use of a working analyzer is presented that is sufficiently simple, rugged, safe and portable to be used under normal clinical conditions to provide a permanent record of the attacks.
Keywords:Monitoring hot flushes  Skin conductance  Skin temperature  Core temperature
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