Monitoring the pathophysiological correlates of postmenopausal hot flushes |
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Authors: | R.W. Silverman J.G. Bajorek P. Lomax I.V. Tataryn |
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Affiliation: | 1. Department of Pharmacology, School of Medicine and the Brain Research Institute, University of California, Los Angeles, CA 90024, U.S.A.;2. Department of Obsterics and Gynecology, University of Alberta, Edmonton, Alberta T6G 2B7, Canada |
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Abstract: | Clinical assessment of the severity and frequency of post-menopausal hot flushes can be made objectively by measuring the associated changes in skin conductance and skin and core temperature. Such measurements provide a more reliable index of the response to therapy than does subjective reporting which has been employed in the past. The design and use of a working analyzer is presented that is sufficiently simple, rugged, safe and portable to be used under normal clinical conditions to provide a permanent record of the attacks. |
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Keywords: | Monitoring hot flushes Skin conductance Skin temperature Core temperature |
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