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| 五种海藻多糖体外抗血小板聚集作用的观察 | |
| 引用本文： | 刘志峰,宫晓黎,魏淑贞.五种海藻多糖体外抗血小板聚集作用的观察[J].中国海洋药物,2001,20(2):36-38. |
| 作者姓名： | 刘志峰 宫晓黎 魏淑贞 |
| 作者单位： | 1. 烟台大学,生化系,烟台,264005 2. 烟台山医院,检验科,264005 3. 青岛市第八人民医院,药剂科,266100 |
| 基金项目： | 山东省科委资助课题（项目编号：991154406） |
| 摘 要： | 本文主要对海带（Ｌａｍｉｎａｒｉａ ｊａｐｅｎｉｏａ Ａｒｅｓｃｈ）、鼠尾藻［Ｓａｒｇａｓｓｕｍ ｔｈｕｎｂｅｒｇｉｌ（Ｍｅｒｔ） ｏ＇Ｋｕｎｔｇｅ］、萱藻［Ｓｃｙｔｏｓｉｐｈｏｎ Ｌｏｍｅｎｔａｒｕｓ（Ｌｙｎｇｂ）Ｊ．Ａｇ］、石莼［Ｕｌｖａ．ｌａｃｔｕｃａｌ］、刚毛［ｃｌａｄｏｐｈｏｒａ ｋｕｔｚｉｎｇ］５种海藻多糖的硫酸基含量以及体外抗血小板聚集作用进行了观察。结果发现，萱藻多糖的硫酸基含量及抗血小板聚集作用显著高于其他海藻多糖，其他依次为鼠尾藻、海带、石莼。刚毛多糖的抗血小板聚集的作用不显著。５种海藻多糖的抗凝血活性与其硫酸基含量是显著正相关。 |
| 关 键 词： | 多糖 硫酸基 血小板聚集 |
| 文章编号： | 1002-3461(2001)02-0036-03 |
| 修稿时间： | 2000年7月26日 |
Observation the effects of five kinds algal polysaccharides on platelets aggregation |
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| LIU Zhi-feng,GONG Xiao-li,WEI Shu-zhen.Observation the effects of five kinds algal polysaccharides on platelets aggregation[J].Chinese Journal of Marine Drugs,2001,20(2):36-38. | |
| Authors: | LIU Zhi-feng GONG Xiao-li WEI Shu-zhen |
| Abstract: | We have observed the effects of five alga polysaccharides on rabbit's blood platelets aggregation. We found that the polysaccharides could inhibit aggregation of blood platelets in vitro. The strongest effect was observed in the polysaccharides from the following,in decreasing order of strength: Scytosiphon lomentarius, Codium fragile,Laminaria japonica and Ulvalactuca. The same effect was not observed in polysaccharides from Cladophra. We also found a positive correlation between the effects of anti-aggregation and the ratio of vitriol radicles in these five polysaccharides. |
| Keywords: | polysaccharide vitriol radicle aggregation of blood platelets |
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