颈动脉粥样硬化斑块稳定性与脑梗死的相关研究

目的探讨颈动脉粥样硬化斑块的稳定性与脑梗死关系。方法对120例脑梗死病人及100例对照组病人行颈动脉超声检查。结果脑梗死组斑块发生率（72．8％）明显高于对照组（56．0％），梗死组不稳定斑块（软斑及溃疡斑）的发生率明显高于对照组（分别为41．1％与18．3％）；梗死侧组软斑及溃疡斑的发生率亦明显高于非梗死侧组，分别为63个（52.1％）与11个（18.6％）（P〈0．05）。脑梗死组〉75％的管腔狭窄数为20例明显高于对照组的3例（，P〈0．05）。结论颈动脉粥样硬化与脑梗死显著相关，颈动脉粥样硬化的程度及斑块的不稳定性是脑梗死的危险因素。

The Stability of Carotid Plaque in Patients with Cerebral Infarction

Objective To assess the stability of carotid plaque in patients with acute cerebral infarction. Methods One hundred and twenty patients (pts)with acute cerebral infarction and 100 control subjects were examined with color dopper ultrasonography. Results The incident of carotid plaque were higher in with cerebral infarction than control subjects (72.8 %vs 56.0%). There was significant difference in the incidence of soft plaque and ulcer plaque between subjects with cerebral infarction(41.1%) and controls (18.3%).the incidence of unstable plaque (soft plaque and ulcer plaque) were higher in infarction side than noninfarction side(51.1%vs 18.6%); The Carotid artery stenosis rate in pts with cerebral infarction were higher than the controls.Conclusion There was a positively relationship between carotid atherosclerosis and cerebral infarction, The level of carotid atherosclerosis and the unstable plaque were risk factor of cerebral infarction.