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扶正健脾法配合化疗对实体瘤患儿生存情况的影响
引用本文:史学,郭秀花,祝秀丹,王焕民,秦红,田莉. 扶正健脾法配合化疗对实体瘤患儿生存情况的影响[J]. 肿瘤研究与临床, 2009, 21(3): 166. DOI: 10.3760/cma.j.issn.1006-9801.2009.03.007
作者姓名:史学  郭秀花  祝秀丹  王焕民  秦红  田莉
作者单位:1. 首都医科大学附属北京儿童医院中医科,100045
2. 首都医科大学公共卫生与家庭医学学院流行病与卫生统计学系
3. 首都医科大学附属北京儿童医院肿瘤外科,100045
基金项目:首都医学科技发展基金 
摘    要: 目的 探讨中医扶正健脾方法配合化疗治疗实体瘤小儿的远期疗效。方法 将2005年1月至2006年3月入组的76例实体瘤患儿随机分为治疗组(35例),对照组(41例)。治疗组采用化疗+自拟扶正健脾中药,对照组采用单纯化疗。结果 治疗组患儿的生存率高于对照组,差异有统计学意义(P=0.0024)。化疗后平均生存时间治疗组(31±2)个月(95 % CI 27~34个月),对照组(21±2)个月(95 % CI 16~25个月),治疗组高于对照组。结论 中医辨证论治、扶正健脾、气血双补,可使患儿体内阴阳气血得以平衡、机体状态比较稳定,能够顺利完成化疗,从而使生存期得以延长。

关 键 词:肿瘤  儿童  中医治疗学  抗肿瘤联合化疗方案  生存率分析
收稿时间:2008-10-06

Effect of Fuzheng Jianpi on survival time in children solid tumors with chemotherapy
SHI Xue,GUO Xiu-hua,ZHU Xiu-dan,WANG Huan-min,QIN Hong,TIAN Li. Effect of Fuzheng Jianpi on survival time in children solid tumors with chemotherapy[J]. Cancer Research and Clinic, 2009, 21(3): 166. DOI: 10.3760/cma.j.issn.1006-9801.2009.03.007
Authors:SHI Xue  GUO Xiu-hua  ZHU Xiu-dan  WANG Huan-min  QIN Hong  TIAN Li
Abstract:Objective To study the effect of traditional Chinese medicine on survival time in children solid tumors with chemotherapy. Methods 76 children with solid tumors, which were collected from January 2005 to March 2006, were randomly divided into treatment group (35 cases), control group (41 cases). The treatment group was treated with chemotherapy + self-dispensing Fuzheng Jianpi Chinese medicine. The control group was treated with chemotherapy alone. Results The survival rate of the treatment group was higher than that of the control group, the difference was statistically significant (P = 0.0024). The average survival time after chemotherapy in the treatment group was (31± 2) months (95 % CI 27-34 months), the control group was (21±2) months (95 % CI 16-25 months), which was shorter than the treatment group.Conclusion Chinese medicine and chemotherapy can prolong the survival time of children with solid tumors.
Keywords:Neoplasms  Child  Therapeutics  Antineoplastic combined chemotherapy protocols  Survival analysis
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