老年无症状动脉硬化的baPWV检测及危险因素分析

目的:探讨老年无症状动脉硬化的检测及危险因素特征。方法:以上臂-脚踝脉搏波传导速度(baPWV)这项与大动脉脉搏波传导速度之间有较好相关性的指标作为测量指标,对204名入住我科的老年人进行baPWV测定,以1400cm/s为界值将所有对象分为对照组与动脉硬化组,比较各危险因素在二组中的分布特征。结果:动脉硬化组的空腹血糖(FBG)、超敏C-反应蛋白(hs-CRP)、尿酸(UA)、收缩压(SBP)、脉压(PP)和体重指数(BMI)均高于对照组,而舒张压(DBP)低于对照组(P<0.05)。Logistic回归显示FBG、hs-CRP、SBP和PP是老年无症状动脉硬化的独立危险因子。结论:FBG、hs-CRP、SBP和PP可能对动脉硬化的发展过程起到促进作用,加强对这些因素的早期预防和干预,有望减少心血管事件的发生。

Detection and Risk Factors Analysis of baPWV in Subclinical Atherosclerosis in Elderly

Objective:To explore the diagnosis and components of subclinical atherosclerosis in elderly patients.Method:A total of 204 hospitalized patients were recruited and devided into subclinical atherosclerosis group and normal control group.Subclinical atherosclerosis was defined as brachial-ankle pulse wave velocity≥1 400 cm/s.Cardiovascular risk factors were measured synchronously and analyzed.Results:FBG,hs-CRP,UA,SBP and PP were higher in subclinical atherosclerosis group than those in normal control group,while DBP was lower(P<0.05).Logistic regression demonstrated that FBG,hs-CRP,SBP and PP were all determinants of subclinical atherosclerosis.Conclusion:FBG,hs-CRP,SBP and PP may be important in accelerated progression of subclinical atherosclerosis.Applying early management on these risk factors may reduce the chances of future cardiovascular events.