| 葡萄糖酸铬对实验性糖尿病小鼠肝PAS反应的影响 |
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| 引用本文： | 李善花,尹哲洙,文香兰,李相伍,文永植.葡萄糖酸铬对实验性糖尿病小鼠肝PAS反应的影响[J].微量元素与健康研究,2005,22(3):7-8. |
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| 作者姓名： | 李善花 尹哲洙 文香兰 李相伍 文永植 |
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| 作者单位： | 1. 延边大学医学院,吉林,延吉,133000
2. 延边州药监局,吉林,延吉,133000 |
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| 摘 要： | 应用PAS反应观察了葡萄糖酸铬治疗的四氧嘧啶性糖尿病小鼠肝糖原变化。实验Ⅰ组铬每日口服剂量为10μg/kg体重,实验Ⅱ组为5μg/kg体重,另设正常对照组及糖尿病对照组。实验周期为4周。结果实验组肝糖原明显增多,实验Ⅰ组更为明显。实验结果提示葡萄糖酸铬可能通过促进肝糖原的合成和周围组织中葡萄糖的利用起到抗糖尿病作用。
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| 关 键 词： | 铬 糖尿病 小鼠 糖原 |
| 文章编号： | 1005-5320(2005)03-0007-02 |
| 修稿时间： | 2005年3月4日 |
Effect of chromium gluconate on the PAS reaction of hepatic tissue of experimental diabetic mice |
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| LI Shan-hua,YIN Zhe-zhu,WEN Xiang-lan,et al.Effect of chromium gluconate on the PAS reaction of hepatic tissue of experimental diabetic mice[J].Studies of Trace Elements and Health,2005,22(3):7-8. |
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| Authors: | LI Shan-hua YIN Zhe-zhu WEN Xiang-lan |
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| Abstract: | With the reaction of PAS, the change of chromium gluconate on hepatic glucogen of diabetic mice induced by alloxan was observed. Experimental groupⅠwas given chromium 10 μg/(kg·d),experimental groupⅡ was given chromium 5 μg/(kg·d),in addition ,normal control group and diabetic control group were set, the experimental period was 4 weeks. The result showed that hepatic glucogen of experimental group was obviously increased, experimental group Ⅰwas more obvious than experimental group Ⅱ. The experimental result indicated that chromium gluconate had effect of anti-diabetic ,maybe by facilitating synthesis of hepatic glucogen and glucose utilization of peripheral tissue. |
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| Keywords: | chromium diabetes mice glucogen |
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