| 电化学预处理银电极对微量白蛋白的电化学响应 |
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| 引用本文： | 于春梅,鲁双云,姜启玉,顾敏华,江文才,张周建,陆宏达,顾海鹰.电化学预处理银电极对微量白蛋白的电化学响应[J].南通医学院学报,2004,24(3):248-250. |
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| 作者姓名： | 于春梅 鲁双云 姜启玉 顾敏华 江文才 张周建 陆宏达 顾海鹰 |
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| 作者单位： | 南通医学院卫生分析化学教研室,南通,226001 |
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| 基金项目： | 中国博士后基金资助项目 ( No.2 0 0 2 0 3 2 186)，江苏省高校自然科学基金资助项目 ( No.0 3 KJB15 0 10 7,JH0 3 -0 41) |
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| 摘 要： | 目的：研究微量白蛋白在电化学预处理银电极上的电化学响应。方法：采用三电极系统，以电化学预处理银电极为工作电极，饱和甘汞电极为参比电极，铂电极为对电极，在-0．1～ 0．3V电位范围内用循环伏安法研究白蛋白的电化学行为。结果：电化学预处理银电极上的白蛋白的循环伏安图出现一对氧化还原峰，还原峰电流与白蛋白浓度在一定范围间呈良好的线性关系。结论：该方法可灵敏测定微量白蛋白，有望用于临床检验及早期诊断糖尿病肾病。
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| 关 键 词： | 微量白蛋白 银电极 电分析化学 |
| 文章编号： | 1000-2057(2004)03-0248-03 |
Electrochemical response of microalbumin at electrochemical pretreated silver electrode |
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| YU Chunmei,LU Shuangyun,JIANG Qiyu,et al.Electrochemical response of microalbumin at electrochemical pretreated silver electrode[J].ACTA Academiae Medicinae Nantong,2004,24(3):248-250. |
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| Authors: | YU Chunmei LU Shuangyun JIANG Qiyu |
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| Abstract: | Objective:To study the electrochemical response of microalbumin at electrochemical pretreated silver electrode.Method:A three-electrode configuration was employed;the working electrode was pretreated silver electrode;the reference and counter electrode were saturated calonael electrode (SCE) and platinum electrode.In potential range of -0.1~+0.3V, cyclic voltammetry(CV) was performed to study the electrochemical behavior of albumin.Results:A pair of redox peaks of BSA were observed respectively and cathodic peak current was proportional to the BSA concentration.Conclusion:This method can detect microalbumin, which can be used in clinic test and early diagnose of diabetic nephropathy. |
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| Keywords: | Microalbumin Silver electrode Electroanalytical chemistry |
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