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检测肝硬化患者血清总胆汁酸水平的临床意义
引用本文:张晓周.检测肝硬化患者血清总胆汁酸水平的临床意义[J].医学综述,2008,14(21):3358-3359.
作者姓名:张晓周
作者单位:陕西正和医院内科,西安,710054
摘    要:目的探讨肝硬化患者中血清胆汁酸(TBA)测定的临床意义。方法收集74例肝硬化患者的肝功能资料,比较TBA与其他常规肝功能指标的敏感性差异。结果肝硬化组的血清TBA显著高于健康对照组(P<0.01),其水平为健康对照组的7.1倍;异常率为75%,显著高于丙氨酸转氨酶、天冬氨酸转氨酶、γ-谷氨酰转肽酶和碱性磷酸酶(P<0.01)。且在不同Child-pugh分级肝硬化患者中,肝功能分级越差,其血清TBA水平越高,提示血清TBA水平与肝细胞损伤的程度呈正相关。结论TBA是反映肝硬化患者肝细胞损害的敏感指标之一,对预测及判断肝硬化预后及病情的严重程度有重要意义。

关 键 词:肝硬化  血清总胆汁酸  肝功能  诊断

Clinical Significance of Total Bile Acid in Serum of Patients with Hepatic Cirrhosis
ZHANG Xiao-zhou.Clinical Significance of Total Bile Acid in Serum of Patients with Hepatic Cirrhosis[J].Medical Recapitulate,2008,14(21):3358-3359.
Authors:ZHANG Xiao-zhou
Institution:ZHANG Xiao- zhou. (Department of internal Medicine, Shanxi Zhenghe Hospital, Xi'an 710054, China )
Abstract:Objective To investigate the significance of total bile acid (TBA)in the serum of patients with hepatic cirrhosis.Methods Data about liver function of 74 cases with hepatic cirrhosis was collected,and the difference of sensitivity between TBA and other conventional liver function index was studied.Results serum TBA of hepatic cirrhosis group is obviously higher than that of healthy control group (P<0.01),Its level is 7.1 fold of the level of healthy control group.the abnormal rate is 75%,and obviously highe...
Keywords:Hepatic cirrhosis  Total bile Acid  Liver function  Diagnosis  
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