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瑞波西汀与氟西汀治疗抑郁症的系统评价
引用本文:杜彪. 瑞波西汀与氟西汀治疗抑郁症的系统评价[J]. 中国医院药学杂志, 2011, 0(6)
作者姓名:杜彪
作者单位:重庆三峡中心医院;重庆三峡精神卫生中心;
基金项目:重庆市科技攻关项目(编号:CSTC,2009AC5195); 重庆市万州区科学技术项目(编号200903008)
摘    要:目的:比较瑞波西汀与氟西汀治疗抑郁症的疗效及不良反应的差异。方法:检索国内关于瑞波西汀与氟西汀对照研究治疗抑郁症的文献,应用系统评价方法对查阅到的9篇进行评估。结果:瑞波西汀与氟西汀的疗效差异无显著性[P>0.05,OR=1.01,95%CI(0.77~1.32)],2组药物不良反应的发生率差异无显著性(P>0.05)。结论:瑞波西汀与氟西汀的疗效治疗抑郁症的疗效和不良反应相似,是一种安全有效的抗抑郁药。

关 键 词:瑞波西汀  氟西汀  抑郁症  系统评价  

Systematic review of reboxetine versus fluoxetine in the treatment for depression
DU Biao. Systematic review of reboxetine versus fluoxetine in the treatment for depression[J]. Chinese Journal of Hospital Pharmacy, 2011, 0(6)
Authors:DU Biao
Affiliation:DU Biao1,2 (1.Chong qing Three Gorges Central Hospital,Chongqing 404000,China,2,Chongqing Three Gorges Mental Health Center,China)
Abstract:OBJECTIVE To compare the difference in therapeutic effects and side effects between reboxetine and fluoxetine.METHODS A total of 9 paper about control study comparing reboxetine with fluoxetine in treatment of depression retrieved from home were subjected to system evaluation.RESULTS There was no significant difference on clinical efficacy between reboxetine group and fluoxetine group [P>0.05,OR=1.0,95%CI(0.77~1.32)].There was also no significant difference of adverse events between reboxetine and fluoxetin...
Keywords:reboxetine  fluoxetine  depression  systematic review  
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