Changes in amylase activity in submandibular salivary glands of puberal male mice following castration. |
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Authors: | M Shear L V Christensen M Haralambous F Barbakow |
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Institution: | Department of Oral Pathology, School of Pathology, University of the Witwatersrand, and South African Institute for Medical Research, Johannesburg, South Africa |
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Abstract: | Left submandibular salivary glands of 33 puberal male Swiss-Webster mice, aged 69 days, were removed for determination of amylase activity and the animals castrated. At 2-week intervals, up to 12 weeks postcastration, the paired right glands were assayed for amylase. Although there was an initial decrease in the mean amylase activity in the experimental gland compared with controls up to 6 weeks postcastration, by 8–12 weeks postcastration it returned to control level. Postcastration levels of amylase activity varied considerably, indicating that its synthesis in the submandibular salivary gland was disturbed, but not permanently suppressed, by castration. |
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