宫颈癌根治术中卵巢移位的价值

背景与目的： 探讨宫颈癌根治术中卵巢移位的价值。材料与方法：对75例45岁以下Ia2～IIb早期宫颈鳞癌患者于根治术中行单侧或双侧卵巢移位，通过血清性激素水平测定和超声检测等方法评估移位术后卵巢功能。结果： 卵巢移位术安全可靠，单侧或双侧卵巢移位后均无移位卵巢发生癌转移现象；移位后未辅加放疗组卵巢功能无明显变化，辅加放疗组雌、孕激素水平虽较未放疗组减低，但仍显著高于根治性放疗组。结论： 45岁以下宫颈癌患者根治术中保留卵巢安全有效，可显著提高患者雌、孕激素水平。

Evaluation of Transposed Ovaries in Cervical Cancer Patients After Surgery and Pelvic Irradiation

BACKGROUND ＆ AIM: To evaluate the value of transposed ovaries in cervical cancer patients after surgery and pelvic irradiation. MATERIAL AND METHODS: In 75 patients with stage Ia2～IIb cervical cancer, 24～45 years of age, Wertheim-Meigs radical hysterectomy was performed with preservation of one or both ovaries transposed outside the pelvis. For evaluation of the post-treatment hormonal function of gonads, serum FSH, LH, estradiol and progesterone levels were assayed after irradiation. RESULTS: The method of transposed ovaries is safety and effective. No patients with retained ovaries developed metastatic disease. The patients who postoperative radiotherapy be indicated occur a substantial loss of ovarian function, but the levels of estradiol and progesterone significantly higher than in the radical therapy group. CONCLUSION: It is our opinion that normal ovaries can be preserved in the women under the age of 45 years at the time of radical hysterectomy for stage Ib～IIb cervical cancer.