Diffuse soft tissue calcification in tumoral calcinosis |
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Authors: | Ella S Feldman MD Murray K Dalinka MD H Ralph Schumacher MD |
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Institution: | (1) The Department of Radiology, Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania, USA;(2) Arthritis-Immunology Center, Veterans Administration Medical Center, University and Woodland Avenues, 19104 Philadelphia, PA, USA |
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Abstract: | Tumoral calcinosis is a rare disease characterized biochemically by hyperphosphatemia, normocalcemia, and reduced fractional excretion of phosphate. Radiographically, it has been defined by the presence of large, amorphous juxtaarticular calcific deposits. A 53-year-old woman with tumoral calcinosis was found to have unusual diffuse soft tissue calcification indistinguishable from that usually seen in collagen vascular disease and previously referred to as calcinosis universalis. It is suggested that tumoral calcinosis is a misnomer as the calcification seen in patients with this disease may be tumoral or diffuse. |
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Keywords: | Tumoral calcinosis Soft tissue calcification Calcinosis universalis Metastatic calcification |
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