吲哚氰绿在外科手术肿瘤荧光中的研究进展

手术是最常用和有效的治疗肿瘤疾病的方法,然而术中肿瘤细胞的残留是术后肿瘤复发、转移的主要因素之一.虽然根据术前的影像学检查及术中快速病理可达到所谓的R0切除,但是对于肉眼无法发现的微小卫星灶及快速病理存在的误差等往往造成肿瘤细胞的残留.因而及时发现残留的肿瘤细胞对于肿瘤患者的预后至为重要.吲哚氰绿是一种新型的可于近红外下术中荧光肿瘤的荧光示踪剂,本文将针对该试剂在肿瘤荧光中的最新进展予以综述.

Advance of indocyanine-green in fluorescent staining tumor in surgical operation

Surgery is so far the most widely used and effective treatment of neoplastic diseases.However,residual tumour cells during surgery remain a major trigger of cancer recurrence and matastasis.Although intraoperative rapid pathological R0 resection can be achieved based on preoperative imageological examination,but for small satellite lesions and the naked eye can not find the error quickly and so often cause pathological presence of residual tumour cells.Thus,quick and accurate identification of residual cancer cells is crucial for prognosis of cancer patients.Indocyanine green (ICG) is a new type of fluorochrome that can stain tumours under the near-infrared fluorescence during surgery,the paper will be reviewed latest developments in the reagent for fluorescence in tumours.