纤维蛋白原和血常规检测对乙型肝炎的诊断价值

目的 探讨纤维蛋白原和血常规检查对乙型肝炎的诊断意义.方法 选取2012年3月-2015年3月来我院就诊确诊为慢性乙型肝炎的患者80例作为观察组,同时收集健康志愿者40例作为对照组.所有研究对象都检测血常规和纤维蛋白原两类指标,具体血常规检测项目包括红细胞(RBC)、血红蛋白(HGB)、白细胞(WBC)、淋巴细胞(LY),纤维蛋白原(Fbg)检测项目包括纤维蛋白单体聚合反应速率(FMPS)、最大吸光度(A-max)、纤维蛋白原含量(FC)、反应延滞时间(DT)、纤维蛋白原功能指数(FI).结果 观察组的红细胞、血红蛋白、白细胞较对照组明显减少(P＜0.05),而淋巴细胞则显著增多(P＜0.05).观察组的FMPS、A-max、FC、DT、FI各项指标较对照组均明显降低(P＜0.05).结论 血常规检测中红细胞、血红蛋白、白细胞、淋巴细胞可作为乙型病毒性肝炎早期筛查指标.血浆纤维蛋白原在一定程度上可反应肝功能状态和肝细胞坏死程度,可作为早期诊断及判断乙型肝炎疾病严重程度的重要指标.

Diagnostic value of fibrinogen and routine blood tests for hepatitis B

Objective To discuss the clinical value of fibrinogen and routine blood test in the diagnosis of hepatitis B.Methods From March 2012 to March 2015,80 patients diagnosed as hepatitis B in our hospital were recruited as the research group and 40 healthy volunteers were recruited as the control group at the same time.Routine blood tests and fibrinogen were analyzed from all research subjects.The indexes of routine blood tests included red blood cell (RBC),hemoglobin (HGB),white blood cells (WBC) and lymphocyte (LY).Fibrinogen tests included FMPS,A-Max,FC,DT and FI.Results RBC,HGB and WBC values of the research group were significantly lower than that of the control group (P ＜ 0.05),while LY was higher (P ＜0.05).FMPS,A-max,FC and DT of the research group were significantly lower than that of the control group (P ＜ 0.05).Conclusions The indexes in routine blood test,including RBC,HGB,WBC and LY can be used for early screening of hepatitis B.Fibrinogen can partly reflect the state of liver function and the degree of liver cell necrosis.It can be used as the criteria of the severity of hepatitis B.