原发髓外浆细胞瘤的研究进展

髓外浆细胞瘤(EMP)是一种罕见肿瘤,特征是浆细胞单克隆增殖,常好发于头颈部,其次是胃肠及皮肤,活检是唯一准确可靠的诊断依据,并且需要与表现相关疾病相鉴别.因EMP有较高的放疗敏感性,故目前以放疗为首选,也可因病情选择综合治疗,而造血干细胞移植因其移植排斥反应,不作为优先选择治疗方案.

Research progress of primary extramedullary plasmacytoma

Extramedullary plasmacytoma (EMP) is a rare tumor characterized by proliferation of monoclonal plasma cells,often occurs in the head and neck,followed by gastrointestinal and skin.Diagnosis is based on biopsy,which is the only accurate and reliable method.EMP is needed to discriminate with similar diseases.Radiotherapy is the preferred treatment method of EMP,because it has a higher radiation sensitivity.Sometime we can choose comprehensive treatment because of illness need.Hematopoietic stem cell transplantation is not as the preferred treatment option because of transplant rejection.