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肌钙蛋白T与CK-MB对急性心肌梗死诊断价值的探讨
引用本文:王卫东,高泽斌,许 方,范琳琳.肌钙蛋白T与CK-MB对急性心肌梗死诊断价值的探讨[J].大连医科大学学报,2007,29(6):587-588+593.
作者姓名:王卫东  高泽斌  许 方  范琳琳
作者单位:1. 大连医科大学,第二临床学院,检验科,辽宁,大连,116027
2. 大连医科大学,检验系,辽宁,大连,116027
摘    要:目的]探讨血清肌钙蛋白T(cTnT)和肌酸激酶同工酶(CK-MB)对急性心肌梗死(AMI)的诊断价值.方法]检测50例因突发胸痛、胸闷及伴有其他临床症状的急诊患者及30例同期非心血管病对照组患者血清肌钙蛋白T和肌酸激酶同工酶的浓度,并进行分析.结果]患者组与对照组间cTnT、cK-MB值差异均有显著性意义.在检测的50例cTnT升高的患者中,心肌梗死的患者36例,占72%,同期CM-MB阳性率低于cTnT.结论]cTnT对心肌梗死的诊断有较高的特异性与敏感性,随着发病时间延长CK-MB的敏感性、特异性逐渐升高.

关 键 词:肌钙蛋白T  肌酸激酶同工酶  急性心肌梗死
文章编号:1671-7295(2007)06-0587-02
收稿时间:2007-07-17
修稿时间:2007-10-21

cTnT and CK-MB' tests results analysis with 50 cases of AMI
WANG Wei-dong,XU Fang and FAN Lin-lin.cTnT and CK-MB'' tests results analysis with 50 cases of AMI[J].Journal of Dalian Medical University,2007,29(6):587-588+593.
Authors:WANG Wei-dong  XU Fang and FAN Lin-lin
Institution:Department of Clinical Laboratory,the Second Affiliated Hospital of Dalian Medical University,Dalian 116027,China;;Department of Clinical Laboratory,the Second Affiliated Hospital of Dalian Medical University,Dalian 116027,China;;Department of Clinical Laboratory,the Second Affiliated Hospital of Dalian Medical University,Dalian 116027,China;;Department of Clinical Laboratory of Dalian Medical University,Dalian 116027,China
Abstract:Objective] To study the value of serum cardiac troponin T(cTnT) and creatine kinase issonzyme MB(CK-MB) in acute myocardial infarction(AMI).Methods] The concentrations of cTnT and CK-MB in 50 cases of sudden chest pain,emergency patients of other systems and 30 cases of non-heart and vessel diseases were detected.Results] cTnT and CK-MB had evident difference between patients and control group.AMI patients covered 72% in 50 cases of patients whose cTnT increased.The positivity rate of CK-MB was lower than cTnT.Conclusion] cTnT has high specificity and sensitivity in the diagnosing AMI.CK-MB's sensitivity and specificity are creasing with the length of time of disease.
Keywords:cardiac troponin T  creatine kinase issonzyme MB  acute myocardial infarction
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