| 远端组织缺血预处理对心脑保护作用的研究进展 |
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| 引用本文： | 翁立军,张野.远端组织缺血预处理对心脑保护作用的研究进展[J].国际麻醉学与复苏杂志,2010,31(3). |
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| 作者姓名： | 翁立军 张野 |
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| 作者单位： | 安徽医科大学第二附属医院麻醉科,合肥,230601 |
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| 摘 要： | 缺血/冉灌注(ischemia reperfusion,I/R)损伤可导致局部和/或远端组织器官的损伤;缺血预处理(ischemic preconditioning,IPC)是对I/R损伤的一种有效处理方式;远端预处理(remote preconditioning,RPC)是继IPC后一种新兴的,更简单又经济的,高效的保护组织器官免受缺血损伤的策略,其机制涉及神经和/或体液两大因素的调节作用,在临床上已有试用.
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| 关 键 词： | 远端预处理 机制 临床应用 |
Advance in protective effects of remote ischemic preconditioning on heart and brain |
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| WENG Li-jun,ZHANG Ye.Advance in protective effects of remote ischemic preconditioning on heart and brain[J].international journal of anesthesiology and resuscitation,2010,31(3). |
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| Authors: | WENG Li-jun ZHANG Ye |
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| Abstract: | Ischemia/reperfusion injury (I/R) results in local and/or remote organ injury. Ischemic preconditioning (IPC) has been shown to protect organs against I/R. Remote ischemic preconditioning (RPC) is a new, easy and convenient strategy to protect organs against I/R by inducing a prior brief period (s) of I/R to an organ remote from that undergoing sustained injury. The mechanisms may involve in regulation of humoral and/or neural factors and this strategy has been applied in clinical trials. |
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| Keywords: | Remote preconditioning Mechanism Clinical application |
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