消瘀定痛散治疗中重度膝关节骨关节炎临床研究

目的评价消瘀定痛散治疗中重度膝关节骨关节炎的临床疗效。方法将符合条件的中重度膝关节骨关节炎患者72例随机分为两组，治疗组给予消瘀定痛散外敷治疗。对照组给予扶他林乳胶剂外涂治疗．治疗前和治疗结束时分别以视觉模拟疼痛评分（VAS）和WOMAC功能评分进行临床评价。结果VAS评分：治疗组治疗前后分别为（6．8±2．2）和（2．1±1．2），对照组治疗前后分别为（6．7±2．4）和（4．8±1．5）。WOMAC功能评分：治疗组治疗前后分别为（63．8±10．2）和（22．3±11．6），对照组分别为（62．7±11．6）和（40．8±12．1），两组比较有统计学意义（P〈0．05），治疗组优于对照组。结论消瘀定痛散可以缓解中重度骨关节炎引起的疼痛，改善膝关节功能，值得推广应用。

The clinical study of xiaoyudingtongsan in treatment of moderate to se- vere knee osteoarthritis

Objective To evaluate the clinical effect of Xiaoyudingtongsan for patients with moderate to severe knee osteoarthritis. Methods Seventy-two cases of moderate to severe knee osteoarthritis were randomly divided into the treatment group（xiaoyudingtongsan） and the control groups（double chlorine acid gel）.The two groups were recorded in pre-treatment and post-treatment pain VAS score, WOMAC scoring standards. Results After treatment, pain VAS score： the treatment group was （2.1±1.2） points, and the control group was （4.8±1.5） points.;WOMAC score ： the treatment group was （22.3± 11.6） points, and the control group was （40.8± 12.1 ） points. The treatment group and control group between groups in comparison VAS score,WOMAC score were significantly different. Conclusion Xiaoyudingtongsan is effective for treating patients with moderate to severe knee osteoarthritis.