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Minimally invasive surgery for oesophageal cancer
Affiliation:Department of Surgery, Academic Medical Center, Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands;Department of Plastic and Reconstructive Surgery, Keio University School of Medicine, 35 Shinanomachi, Shinjuku-ward, Tokyo 160-8582, Japan;University of Southern California, Laboratory of Applied Pharmacokinetics;University of Southern California, Ostrow School of Dentistry;Department of Thoracic Surgery, Anhui Provincial Hospital affiliated with Anhui Medical University, Hefei, Anhui Province, China;Leeds Institute of Cancer & Pathology, Wellcome Trust Brenner Building, St James’ University Hospital, Leeds, West Yorkshire LS9 7TF, UK;Department of Oto-rhinolaryngology, Head and Neck Surgery and Audiology, Rigshospitalet, Copenhagen, Denmark;Department of Dermato-Allergology, Gentofte Hospital, University of Copenhagen, Copenhagen, Denmark;Department of Pathology, Rigshospitalet, Copenhagen, Denmark;Institute for Cellular and Molecular Medicine, University of Copenhagen, Copenhagen, Denmark;Department of Oto-rhinolaryngology, Head and Neck Surgery and Audiology, Rigshospitalet, Copenhagen, Denmark
Abstract:Worldwide an increasing part of oncologic oesophagectomies is performed in a minimally invasive way. Over the past decades multiple reports have addressed the perioperative outcomes and oncologic safety of minimally invasive oesophageal surgery. Although many of these (retrospective) case–control studies identified minimally invasive oesophagectomy as a safe alternative to open techniques, the clear benefit remained subject to debate. Recently, this controversy has partially resolved due to the results of the first randomized controlled trial that compared both techniques. In this trial short-term benefits of minimally invasive oesophagectomy were demonstrated in terms of lower incidence of pulmonary infections, shorter hospital stay and better postoperative quality of life. However, the current lack of long-term data on recurrence rate and overall survival precludes a comprehensive comparison of minimally invasive and open oesophagectomy. Proclaiming minimally invasive oesophagectomy as the standard of care for patients with resectable oesophageal cancer would therefore be a premature decision.
Keywords:Oesophageal cancer  Minimally invasive surgery  Oesophagectomy  Thoracoscopy  Laparoscopy
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