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Positive and cost-effectiveness effect of spa therapy on the resumption of occupational and non-occupational activities in women in breast cancer remission: A French multicentre randomised controlled trial
Affiliation:1. Department of Public Health of Clermont-Ferrand Hospital University Hospital, 7 Place Henri Dunant, 63000 Clermont Ferrand, France;2. Clermont Université, Université d''Auvergne, EA 4681, PEPRADE, F-63000 Clermont-Ferrand, France;3. Department of Oncogenetics, Comprehensive Anticancer Centre Jean Perrin, 58 Rue Montalembert, 63000 Clermont-Ferrand, France;1. Universidade do Estado de Santa Catarina, Florianópolis, Santa Catarina, Brazil;2. Exercise and Health Lab, Faculdade de Motricidade Humana, Universidade de Lisboa, Portugal;3. Universidade Federal de Santa Catarina, Florianópolis, Santa Catarina, Brazil;1. Centre de recherche rhumatologique et thermal, 15, avenue Charles-de-Gaulle, 73100 Aix-les-Bains, France;2. Inserm CIC03, centre for clinical investigation, 38000 Grenoble, France;3. University of Jyväskylä, Jyväskylä, Finland;4. 13, avenue des Thermes-Athéna, 34540 Balaruc-les-Bains, France;5. Université de Toulouse, 31000 Toulouse, France;1. Rheumatology Unit, Azienda Ospedaliera Universitaria Senese, “Le Scotte” Policlinico, Viale Bracci 1, 53100 Siena, Italy;2. Department of Medical Ecology and Hydroclimatology, Istanbul Medical Faculty, Istanbul University, Istanbul, Turkey;3. Polyclinic of the Hospitaller Brothers of St. John of God, Budapest, Hungary;1. University of Alberta, Canada;2. Athabasca University, Canada;3. Cross Cancer Institute, Canada;1. Vascular Diseases Center, Unit, University of Ferrara, Ferrara, Italy;2. Rehabilitation Unit, Department of Neuroscience, University of Padua, Padua, Italy;3. Angiology Unit, Department of Cardiac, Thoracic and Vascular Sciences, Padova University Hospital, Padova, Italy;4. Department of Surgery Uniformed Services University of the Health Sciences, Bethesda, Md
Abstract:Purpose of the researchThe main aim was to assess the effects of a spa treatment on the resumption of occupational and non-occupational activities and the abilities of women in breast cancer remission. A cost-effectiveness analysis (CEA) was also performed.Methods and sampleA multicentre randomised controlled trial was carried out between 2008 and 2010 in the University Hospital of Auvergne and two private hospitals in Clermont-Ferrand, France. Eligible patients were women in complete breast cancer remission without contraindication for physical activities or cognitive disorders and a body mass index between 18.5 and 40 kg/m2. The intervention group underwent spa treatment combined with consultation with dietician whereas the control underwent consultations with the dietician only. Of the 181 patients randomised, 92 and 89 were included in the intervention and the control groups, respectively. The CEA involved 90 patients, 42 from the intervention group and 48 from the control group.Key resultsThe main results showed a higher rate of resumption of occupational activities in the intervention group (p = 0.0025) and a positive effect of the intervention on the women's ability to perform occupational activities 12 months after the beginning of the study (p = 0.0014), and on their ability to perform family activities (p = 0.033). The stay in a thermal centre was cost-effective at 12 months.ConclusionsSpa treatment is a cost-effective strategy to improve resumption of occupational and non-occupational activities and the abilities of women in breast cancer remission.
Keywords:Oncology  Breast cancer  Randomised controlled trial  Work resumption  Spa therapy
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