Neuromuscular disorders: relevance to anaesthesia and intensive care |
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| Institution: | 1. Department of Clinical Immunology, Wroclaw Medical University;2. ALL-MED Medical Research Institute, Wroclaw, Poland;3. Swiss Institute of Allergy and Asthma Research (SIAF), University of Zurich, Davos, Switzerland;4. Department of Allergy & Clinical Immunology, Transylvania University, Brasov, Romania;5. Faculty of Veterinary Medicine, University of Kirikkale, Kirikkale, Turkey. Conflict of interest: MJ serves as a consultant to Allergopharma, Biomay and Anergis. MJ received lecture fees from Allergo-pharma, Stallergens, GlaxoSmithKline, AstraZeneca and Aventis. |
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| Abstract: | Although relatively rare, neuromuscular disease is important to both anaesthetists and intensivists as it may complicate general anaesthesia and result in neurogenic respiratory failure. The most common diseases that will be encountered in a general anaesthetic practice include motor neurone disease, Guillain–Barré syndrome, botulism, myasthenia gravis and the muscular dystrophies. The clinical features and anaesthetic implications for these conditions are discussed. |
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| Keywords: | Anaesthesia motor neurone disease neuromuscular disease neuromuscular junction Guillain–Barré botulism myasthenia gravis muscular dystrophy |
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