Sequence of a rat immunoglobulin gamma 2c heavy chain constant region cDNA: extensive homology to mouse gamma 3 |
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| Authors: | M Brüggemann P Delmastro-Galfrè H Waldmann F Calabi |
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| Affiliation: | Department of Pathology, University of Cambridge, GB. |
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| Abstract: | The complete sequence of the rat immunoglobulin gamma 2c heavy chain constant region has been determined by cDNA cloning and by mRNA sequencing. Comparison with other heavy chain genes reveals a high degree of homology (87%) to mouse gamma 3 and suggests that rat and mouse gamma genes separated from a common set of three ancestral genes. |
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