Antimicrobial and Cytotoxic Activity of Some Medicinal Plants from Baja California Sur (Mexico) |
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| Authors: | DR Encarnación SG Franzblau |
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| Institution: | 1. Universidad Autonoma de Baja California Sur, Departamento de Agronomia, La Paz, Mexico;2. Pharmacology Research Department, Laboratory Research Branch, Gillis W. Long Hansen's Disease Center, Baton Rouge, Louisiana, USA |
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| Abstract: | Scientific evaluation of 25 ethanol extract of plants used in the traditional medicine of Baja California Sur (Mexico) were tested for microbial and HCT-116 cell growth inhibition. Ten extracts showed activity against the HCT-116 cell line, notably Asclepias subulata (Asclepiadaceae), Aristolochia brevipes (Aristolochiaceae) and Bursera odorata (Burseraceae). Haplopappus sonorensis (Asteraceae) Asclepias subulata and Bursera odorata inhibited Mycobacterium tuberculosis by 40, 45 and 67%, respectively, at a concentration of 100 µg/mL. Antimicrobial activity against Bacillus subtilis, Staphylococcus aureus, Streptococcus faecalis, Candida albicans and Escherichia coli was determined, and Aristolochia monticola, A. brevipes, Hymenoclea monogyra and Hymenoclea sp. were found to be the most active. Xanthium strumarium showed low activity against C. albicans. |
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| Keywords: | Adansonia digitata Bombaceae 13C NMR epicatechin 1H NMR procyanidin B2 procyanidin B5 procyanidin C1 Procyanidins proanthocyanidins A2 |
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