广西高中生乙肝病毒感染率影响因素调查

目的了解广西高中生乙肝高发的原因,为有关部门制定乙肝防控策略和措施提供科学依据。方法采用自行设计的流行病学调查问卷,分层随机整群抽取广西2 632名高一至高三学生进行问卷调查。调查内容包括一般人口学资料、生活习惯、病毒性肝炎患病史、病毒性肝炎防治知识知晓情况和乙肝疫苗接种史等。结果 2 632名学生中,乙肝表面抗原(HBsAg)阳性192名,阳性率为7.29%。单因素χ~2检验结果发现,学生HBsAg阳性率的高低与家庭成员有无肝炎史、学生有无美容美发外伤史、本人是否接种过乙肝疫苗、对乙肝知识的知晓情况(传播途径、传染源以及乙肝治疗结局)有关。多因素分析结果显示,家庭成员具有肝病病史和学生美容美发外伤史与乙肝感染呈正性相关(OR=3.62,95%CI=2.28～5.73; OR=3.06,95%CI=1.94～4.83),乙肝疫苗接种史与乙肝感染呈负性相关(OR=0.08,95%CI=0.05～0.11)。结论广西高中生乙肝病毒感染可能与乙肝疫苗接种缺失、美容创伤及家庭接触有关。

Correlates of HBV infection among high school students in Guangxi

Objective To understand hepatitis B virus(HBV)infection in high school students in Guangxi,and to provide scientific foundation for hepatitis B prevention and control strategies.Methods A self-designed epidemiological questionnaire was used among 2 632 participants.Information regarding general demographic characteristics,lifestyle habits,HBV infection history, knowledge of viral hepatitis prevention and control,as well as hepatitis B vaccination.Univariate and multivariate logistics regression analysis was used to analyze associated factors for hepatitis B infection.Results A total of 192 out of 2 632 participants were found HBsAg positive and 2 440 were HBsAg negative.Multivariate analysis showed that family liver disease history and hairdressing injury positively associated with hepatitis B virus infection risk (OR=3.62,95%CI=2.28-5.73;OR=3.06,95%CI=1.94- 4.83),and hepatitis B vaccination was negatively associated with hepatitis B virus infection risk (OR =0.08,95%CI=0.05-0.11). Conclusion Family history of liver disease,hairdressing injury experiences,as well as low rate of hepatitis B vaccination may asso- ciate with relatively high prevalence of hepatitis B virus infection among high school students in Guangxi.