中西医结合治疗小儿肾炎肾病型紫癜性肾炎远期疗效观察

应用中西医结合方法治疗21例肾炎肾病型紫癜性肾炎疗效满意,有16例痊愈或完全缓解,5例部分缓解。平均随访7.34年,未发现有肾功能不全者。应用雷公藤多甙配合中药或加强的松的治疗方法较好,副作用少。积极防治上呼吸道感染。对减少病情反复起重要作用。

Long-Term Effect of Schonlein-Henoch Nephritis with Nephritic-Nephrotic Syndrome in Children by TCM-WM

21 cases are fully agreed with the diagnosis standard of Schonlein-Henoch nephritis. Biopsy on the kidney of 5 cases with resistant duration was made and all were diagnosed as mesenteric hyperplastic glomerular nephritis, among them, one with segemental sclerosis, one with segemental sclerosis and cresents in some glomerulus. 13 cases were treated with prednisone, cyclophosphamide and Traditional Chinese herbs. 8 cases with wilfordine adding and /or traditional Chisese herbs. The results showed that 15 of 21 cases were cured, one case perfect remission, 4 cases part remission. All of the cases were followed-up from 2 years and 10 months to 12 years and 4 months, average 7.34 years. The late results: GroupA, 16 cases with symptom, physical exam, urine routine normal. Group B, 4 cases with microscopic hematuria ahd/or"a little " urinary protein. Group C, one case With " " urinary protein and/or hypertension, urinary creatinine clearance rate normal. Of 5 cases, whose biopsies of kidney were made, one with glomerular segemental sclerosis belonged to Group 6. 13 of 21 cases had recurrened for 1-6 times, which was closed related with uprespiratory tract infection.