| 慢肾康胶囊对大鼠C-BSA肾炎的治疗作用观察 |
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| 引用本文： | 周爱香,李小芹,吴子伦,何伟,贺蓉,宗桂珍,李德风,郭淑英.慢肾康胶囊对大鼠C-BSA肾炎的治疗作用观察[J].中国实验方剂学杂志,2002,8(2):34-38. |
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| 作者姓名： | 周爱香 李小芹 吴子伦 何伟 贺蓉 宗桂珍 李德风 郭淑英 |
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| 作者单位： | 中国中医研究院中药研究所,北京,100700 |
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| 摘 要： | 以慢肾康胶囊 8 4、4 2、2 1g生药 kg连续灌胃给予c BSA肾炎大鼠 4周 ,观察尿蛋白含量 ,血清白蛋白、胆固醇、肌酐、尿素氮 ,病理学 ,免疫荧光等 ,多项指标结果显示慢肾康胶囊对C BSA肾炎大鼠有明显的治疗作用 ;能明显抑制小鼠体液免疫 ,对细胞免疫无明显影响 ,对 10 %高分子右施糖酐所致家免微循环障碍有显著的保护作用
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| 关 键 词： | 慢肾康胶囊 CBSA肾炎 体液免疫 |
| 文章编号： | 1005-9903(2002)02-0034-05 |
| 收稿时间： | 2/6/2001 12:00:00 AM |
| 修稿时间： | 2001年2月6日 |
Therapeutic Action of Manshen Kang Capsule on C-BSA Nephritis Rats |
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| ZHOU Ai-xiang,LI Xiao-qin,WU Zi-lun,HE Wei,HE Rong,ZONG Gui-zhen,LI De-feng,GUO Shu-ying.Therapeutic Action of Manshen Kang Capsule on C-BSA Nephritis Rats[J].China Journal of Experimental Traditional Medical Formulae,2002,8(2):34-38. |
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| Authors: | ZHOU Ai-xiang LI Xiao-qin WU Zi-lun HE Wei HE Rong ZONG Gui-zhen LI De-feng GUO Shu-ying |
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| Institution: | Institute of Chinese Materia Medica, China Academy of Traditional Chinese Medicine, Beijing 100700 |
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| Abstract: | Urea protein content, serum albumin, cholesterol, creatinine, urea nitrogen, histopathology, et al were observed in C\|BSA nephritis rats which were orally administrated with Manshen Kang Capsule 8 4,4 2,2 1 g/kg for 4\|week, respectively. The results showed the capsule had significant therapeutic action on C\|BSA nephritis rats, could inhibit mice humoral immunity, but no effect on cell mediated immunity. In addition, the capsule had markedly protective effect of rabbit's microcirculation obstruction induced by 10% macromolecule intradex. |
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| Keywords: | Manshen Kang Capsule C\|BSA nephritis Humoral immunity |
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