乳腺癌肝转移的外科治疗

目的探讨乳腺癌肝转移外科治疗的价值。方法回顾性分析1997年5月至2000 年5月我院手术治疗的18例乳腺癌肝转移患者的治疗过程和预后情况。结果本组肝转移多发生在乳腺癌原发灶切除24～36个月以后,占66．7％,合并肝内多发转移灶者11例,单发病灶7例。 18例患者均行外科手术切除肝转移灶。单灶与多灶肝转移3年生存率分别为83．3％和54．5％(P= 0．037)。结论在无其他脏器转移时乳腺癌肝转移的外科治疗的效果与肝转移灶数目相关,与肝转移灶的体积大小,及乳腺癌原发灶的分期无相关性,积极的外科治疗是提高患者生存率的有效方法之一。

Surgical treatment of liver metastases of breast cancer

Objective To evaluate hepatectomy for liver metastasis in breast cancer patients. Methods From May 1997 to May 2000, 18 primary breast cancer patients with metachronous liver metastases underwent hepatectomy. The clinicopathologic features and surgical results were analyzed. Results The actuarial 1,3-year survival rates after hepatic resection were 100% and 83. 3% for patients with solitary metastasis, and 90.9% and 54.5% for those with multiple foci. Conclusions Posthepatectomy long term survival was correlated with the number of foci in postmastectomy breast cancer patients suffering from heterochronous liver metastasis. Tumor size and TNM stage of breast cancer were not correlated with the survival. Aggressive surgery helps to prolong the survival.