双侧原发性乳腺癌24例报告

从1958年1月至1988年12月,收治女性乳腺癌1020例,经病理证实双侧原发性乳腺癌24例(2.35％)。平均年龄43岁。3例有癌家族史。同时性和异时性者分别为6例及18例。二癌相距平均6.3年。大多数患者作乳房根治术,5例行单纯乳房切除术。异时性患者的5,10,15和20年生存率分别为81.25％,78.75％,50.0％和30.0％,而同时性患者仅1例生存4年健在。

Bilateral Primary Breast Cancer,A Report of 24 Cases

There were 1020 female patients with breast cancer that were treated in our hospital from January 1958 to Decem- ber 1988. Of these 24 (2.35%)were pathologically proven as bilateral primaries. The average age of the latter group was 43 years. Three had family history of cancer. Six and eighteen patients were synchronous and asynchronous bilateral breast cancer respectively. The average duration of elapse from the first cancer to the discovery of the second one was 6.3 years. Most of the patients were operated with radical mastectomy,only 5 underwent simple mastectomy. Following the treatment the 5,10,15,20 years survival rates of asynchronous patients were 81.25%, 78.75%,50.0%, and 30.0% respectively. In synchronous cases, only one survived free of disease at 4 years, the rest died of recurrence within 5 years.