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正交试验优选滋肾养阴颗粒提取工艺
引用本文:陈占立,孙爱平,石润波,李知遥,魏学君,李正杰.正交试验优选滋肾养阴颗粒提取工艺[J].中国药房,2009(15):1147-1148.
作者姓名:陈占立  孙爱平  石润波  李知遥  魏学君  李正杰
作者单位:河北医科大学医药研究院,石家庄市050035
摘    要:目的:优选滋肾养阴颗粒的最佳提取工艺。方法:以出膏率和80%乙醇浸出物含量为指标,以提取次数、提取时间、加水量为考察因素,采用正交试验优选提取工艺。结果:优选出的提取工艺为加水煎煮3次,煎煮时间依次为3、2、1h,加水量依次为9、6、6倍量。结论:优选的工艺节省时间、节约能源,适合大生产。

关 键 词:滋肾养阴颗粒  正交试验  提取工艺

Optimization of the Extraction Technology of Zishen Yangyin Granules by Orthogonal Experiment
CHEN Zhan-li,SUN Ai-ping,SHI Run-bo,LI Zhi-yao,WEI Xue-jun,LI Zheng-jie.Optimization of the Extraction Technology of Zishen Yangyin Granules by Orthogonal Experiment[J].China Pharmacy,2009(15):1147-1148.
Authors:CHEN Zhan-li  SUN Ai-ping  SHI Run-bo  LI Zhi-yao  WEI Xue-jun  LI Zheng-jie
Institution:(Hebei Institute of Medicine and Medical University,Shijiazhuang 050035, China)
Abstract:OBJECTIVE: To optimize the extraction technology of Zishen yangyin granules. METHODS: The yield of the extraetum and the content of the extraction using 80% alcohol as solvent were used as indexes to optimize the extraction technology of Zishen yangyin granules by orthogonal experiment with the times of extraction, the extraction time and the amount of water added as factors. RESULTS: The optimal extraction conditions were as follows: the extraction was carried out for 3 times by adding water at an amount of 9 times, 6 times and 6 times, respectively that of solid substance with decoction time of 3 h, 2 h and 1 h, respectively. CONCLUSION: The optimal extraction process was proved to be time - saving and energy-saving and suitable for large production.
Keywords:Zishen yangyin granules  Orthogonal experiment  Extraction technology
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