| 益神颗粒质量标准研究 |
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| 引用本文： | 沈洁,任世禾,车京梅.益神颗粒质量标准研究[J].中国药房,2009(21):1649-1651. |
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| 作者姓名： | 沈洁 任世禾 车京梅 |
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| 作者单位： | 上海市中医医院,上海市200071 |
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| 摘 要： | 目的:建立益神颗粒的质量标准。方法:采用薄层色谱(TLC)法对制剂中的制何首乌、灵芝、黄芪、当归进行定性鉴别;用高效液相色谱法对制何首乌中二苯乙烯苷进行含量测定。结果:TLC鉴别方法专属性强,在与对照药材/对照品相应的位置上显相同颜色的斑点,阴性对照无干扰。二苯乙烯苷进样量在0.037 75~0.755μg范围内与峰面积积分值呈良好线性关系(r=0.999 5);平均加样回收率为99.44%,RSD=1.79%(n=6)。结论:所建标准可用于益神颗粒的质量控制。
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| 关 键 词： | 益神颗粒 质量标准 二苯乙烯苷 薄层色谱法 高效液相色谱法 |
Quality Standard of Yishen Granules |
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| SHEN Jie,REN Shi-he,CHE Jing-mei.Quality Standard of Yishen Granules[J].China Pharmacy,2009(21):1649-1651. |
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| Authors: | SHEN Jie REN Shi-he CHE Jing-mei |
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| Institution: | (Shanghai Hospital of TCM, Shanghai 200071, China) |
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| Abstract: | OBJECTIVE： To establish the quality standard of Yishen granules. METHODS：Polygonurn multiflorurn ,Ganoderma,Radix Astragali and Angelica sinensis in the formulation were identified by TLC. The content of stilbene glucoside in polygonurn multiflorum was determined by HPLC. RESULTS： The TLC identification method exhibited good specificities. The samples were similar to the references/control in that their TLC spots assumed identical color at the corresponding places, yet without the interference form the negative samples. The linear range of stilbene glucoside was 0.037 75-0.755μg（r = 0.999 5） and the average recovery was 99.44% （RSD = 1.79%, n = 6） . CONCLUSION： The established standard is accurate, reliable and applicable for the quality control of Yishen granules. |
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| Keywords: | Yishen granules Quality standard Stilbene glucoside TLC HPLC |
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