我院慢性阻塞性肺疾病住院患者抗菌药物应用分析

目的:了解我院慢性阻塞性肺疾病(COPD)患者抗菌药物的应用情况。方法:采用回顾性调查方法,对我院77例COPD住院患者抗菌药物的应用种类、频率、费用、给药途径、给药时间、联用情况、治疗结果、细菌培养和药敏试验、不良反应、不合理应用等情况进行统计、分析。结果:抗菌药物应用率达100.00%;应用频率排序列前5位的分别为左氧氟沙星、头孢呋辛、阿莫西林/克拉维酸钾、头孢他啶、阿奇霉素;二联用药占77.65%;三联用药占2.35%。结论:我院COPD住院患者抗菌药物应用基本合理,但还需严格掌握抗菌药物的适应证,针对性用药,使COPD患者抗菌药物应用更加合理、规范。

Application of Antibacterials for the Inpatients with Chronic Obstructive Pulmonary Disease in Our Hospital

OBJECTIVE： To investigate the application of antibacterials in patients with chronic obstructive pulmonary disease （COPD） in our hospital. METHODS： A retrospective analysis was performed on 77 COPD inpatients with respect to the varieties of antibiotics, DDDs, drug costs, routes of administration, medication duration, combined use of antibiotics, therapeutic outcome, bacterial culture and susceptibility test, adverse drug reactions （ADR） and irrational drug use etc. RESULTS： 100% of the patients received antibacterials. Topping the first five places on the DDDs list were levofloxacin, cefuroxime, amoxicillin/clavulanate potassium, ceftazidime and azithromycin. The combined use of two kinds of antibiotics accounted for 77.65% versus 2.35% of three kinds concomitantly. CONCLUSION： The use of antibacterials in COPD patients in our hospital is basically rational; however, the indications of antibacteriats for COPD patients should be followed strictly toachieve rational and standard drug use.